5jo3

<table><tr><td colspan='2'>[[5jo3]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JO3 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5JO3 FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6LK:1-(5-CHLORO-6-METHOXYPYRIDIN-3-YL)-3-METHYL-N-(METHYLSULFONYL)-1H-INDAZOLE-5-CARBOXAMIDE'>6LK</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3',5'-cyclic-GMP_phosphodiesterase 3',5'-cyclic-GMP phosphodiesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.4.35 3.1.4.35] </span></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5jo3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jo3 OCA], [http://pdbe.org/5jo3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jo3 RCSB], [http://www.ebi.ac.uk/pdbsum/5jo3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jo3 ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/PDE5A_HUMAN PDE5A_HUMAN]] Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP.

[[Category: 3',5'-cyclic-GMP phosphodiesterase]]

[[Category: Chrencik, J]]

[[Category: Storer, I]]

[[Category: Hydrolase]]