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5jo3
From Proteopedia
(Difference between revisions)
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<StructureSection load='5jo3' size='340' side='right'caption='[[5jo3]], [[Resolution|resolution]] 1.49Å' scene=''> | <StructureSection load='5jo3' size='340' side='right'caption='[[5jo3]], [[Resolution|resolution]] 1.49Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5jo3]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JO3 OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5jo3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JO3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JO3 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6LK:1-(5-CHLORO-6-METHOXYPYRIDIN-3-YL)-3-METHYL-N-(METHYLSULFONYL)-1H-INDAZOLE-5-CARBOXAMIDE'>6LK</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.49Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6LK:1-(5-CHLORO-6-METHOXYPYRIDIN-3-YL)-3-METHYL-N-(METHYLSULFONYL)-1H-INDAZOLE-5-CARBOXAMIDE'>6LK</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jo3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jo3 OCA], [https://pdbe.org/5jo3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jo3 RCSB], [https://www.ebi.ac.uk/pdbsum/5jo3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jo3 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/PDE5A_HUMAN PDE5A_HUMAN] Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP. |
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Chrencik | + | [[Category: Chrencik J]] |
| - | [[Category: Storer | + | [[Category: Storer I]] |
| - | + | ||
Current revision
PDE5A for NaV1.7
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