5jr0

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==Domain 4 Segment 6 of voltage-gated sodium channel Nav1.4==
==Domain 4 Segment 6 of voltage-gated sodium channel Nav1.4==
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<StructureSection load='5jr0' size='340' side='right'caption='[[5jr0]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
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<StructureSection load='5jr0' size='340' side='right'caption='[[5jr0]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5jr0]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JR0 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5JR0 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5jr0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JR0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JR0 FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solid-state NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5jr0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jr0 OCA], [http://pdbe.org/5jr0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jr0 RCSB], [http://www.ebi.ac.uk/pdbsum/5jr0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jr0 ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jr0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jr0 OCA], [https://pdbe.org/5jr0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jr0 RCSB], [https://www.ebi.ac.uk/pdbsum/5jr0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jr0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SCN4A_RAT SCN4A_RAT]] This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. This sodium channel may be present in both denervated and innervated skeletal muscle.<ref>PMID:2559760</ref>
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[https://www.uniprot.org/uniprot/SCN4A_RAT SCN4A_RAT] This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. This sodium channel may be present in both denervated and innervated skeletal muscle.<ref>PMID:2559760</ref>
==See Also==
==See Also==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Egawa, A]]
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[[Category: Rattus norvegicus]]
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[[Category: Fujiwara, T]]
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[[Category: Egawa A]]
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[[Category: Ikeda, K]]
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[[Category: Fujiwara T]]
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[[Category: Niitsu, A]]
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[[Category: Ikeda K]]
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[[Category: Tachibana, K]]
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[[Category: Niitsu A]]
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[[Category: Alpha-helix]]
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[[Category: Tachibana K]]
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[[Category: Metal binding protein]]
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[[Category: Protein fragment]]
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[[Category: Transmembrane]]
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Revision as of 19:02, 20 September 2023

Domain 4 Segment 6 of voltage-gated sodium channel Nav1.4

PDB ID 5jr0

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