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5jwc

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Current revision (19:12, 20 September 2023) (edit) (undo)
 
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<StructureSection load='5jwc' size='340' side='right'caption='[[5jwc]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
<StructureSection load='5jwc' size='340' side='right'caption='[[5jwc]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5jwc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plaf7 Plaf7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JWC OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5JWC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5jwc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JWC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JWC FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4W0:5-FLUORO-3-METHYL-2-{4-[4-(TRIFLUOROMETHOXY)BENZYL]PHENYL}QUINOLIN-4(1H)-ONE'>4W0</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TRT:FRAGMENT+OF+TRITON+X-100'>TRT</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.051&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5jwa|5jwa]], [[5jwb|5jwb]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4W0:5-FLUORO-3-METHYL-2-{4-[4-(TRIFLUOROMETHOXY)BENZYL]PHENYL}QUINOLIN-4(1H)-ONE'>4W0</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TRT:FRAGMENT+OF+TRITON+X-100'>TRT</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PFI0735c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=36329 PLAF7])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jwc OCA], [https://pdbe.org/5jwc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jwc RCSB], [https://www.ebi.ac.uk/pdbsum/5jwc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jwc ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NADH_dehydrogenase NADH dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.99.3 1.6.99.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5jwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jwc OCA], [http://pdbe.org/5jwc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jwc RCSB], [http://www.ebi.ac.uk/pdbsum/5jwc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jwc ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8I302_PLAF7 Q8I302_PLAF7]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: NADH dehydrogenase]]
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[[Category: Plasmodium falciparum 3D7]]
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[[Category: Plaf7]]
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[[Category: Yu Y]]
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[[Category: Yu, Y]]
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[[Category: Inhibitor]]
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[[Category: Malaria]]
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[[Category: Membrane protein]]
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[[Category: Ndh2]]
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[[Category: Pfndh2]]
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[[Category: Plasmodium falciparum]]
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Current revision

Structure of NDH2 from plasmodium falciparum in complex with RYL-552

PDB ID 5jwc

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