7xb7

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Current revision (06:50, 27 September 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 7xb7 is ON HOLD until Paper Publication
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==Phosphoglycerate mutase 1 complexed with a covalent inhibitor==
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<StructureSection load='7xb7' size='340' side='right'caption='[[7xb7]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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Authors: Jiang, L.L., Zhou, L.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7xb7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XB7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XB7 FirstGlance]. <br>
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Description: Phosphoglycerate mutase 1 complexed with a covalent inhibitor
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CKF:3-[[5-(cyclopenten-1-yl)-2-(methylcarbamoyl)phenyl]sulfamoyl]benzenesulfonic+acid'>CKF</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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[[Category: Zhou, L]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xb7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xb7 OCA], [https://pdbe.org/7xb7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xb7 RCSB], [https://www.ebi.ac.uk/pdbsum/7xb7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xb7 ProSAT]</span></td></tr>
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[[Category: Jiang, L.L]]
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PGAM1_HUMAN PGAM1_HUMAN] Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity.
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Jiang LL]]
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[[Category: Zhou L]]

Current revision

Phosphoglycerate mutase 1 complexed with a covalent inhibitor

PDB ID 7xb7

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