8b3c

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Current revision (06:52, 27 September 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8b3c is ON HOLD until Paper Publication
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==chalcone synthase from Hordeum vulgare complexed with malonyl-CoA==
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<StructureSection load='8b3c' size='340' side='right'caption='[[8b3c]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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Authors: Zhang, L., Groves, M.R.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8b3c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Hordeum_vulgare Hordeum vulgare]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8B3C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8B3C FirstGlance]. <br>
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Description: chalcone synthase from Hordeum vulgare complexed with malonyl-CoA
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=ERD:(2S)-2-(3,4-DIHYDROXYPHENYL)-5,7-DIHYDROXY-2,3-DIHYDRO-4H-CHROMEN-4-ONE'>ERD</scene></td></tr>
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[[Category: Zhang, L]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8b3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8b3c OCA], [https://pdbe.org/8b3c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8b3c RCSB], [https://www.ebi.ac.uk/pdbsum/8b3c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8b3c ProSAT]</span></td></tr>
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[[Category: Groves, M.R]]
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CHS2_HORVU CHS2_HORVU] The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin. Substrate preference is feruloyl-CoA = caffeoyl-CoA >> cinnamoyl-CoA.
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__TOC__
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</StructureSection>
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[[Category: Hordeum vulgare]]
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[[Category: Large Structures]]
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[[Category: Groves MR]]
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[[Category: Zhang L]]

Current revision

chalcone synthase from Hordeum vulgare complexed with malonyl-CoA

PDB ID 8b3c

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