4xk4
From Proteopedia
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<StructureSection load='4xk4' size='340' side='right'caption='[[4xk4]], [[Resolution|resolution]] 2.27Å' scene=''> | <StructureSection load='4xk4' size='340' side='right'caption='[[4xk4]], [[Resolution|resolution]] 2.27Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4xk4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[4xk4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XK4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XK4 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.27Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DUC:DIHYDROPYRIMIDINE-2,4(1H,3H)-DIONE'>DUC</scene></td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xk4 OCA], [https://pdbe.org/4xk4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xk4 RCSB], [https://www.ebi.ac.uk/pdbsum/4xk4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xk4 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xk4 OCA], [https://pdbe.org/4xk4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xk4 RCSB], [https://www.ebi.ac.uk/pdbsum/4xk4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xk4 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/RUTR_ECOLI RUTR_ECOLI] Master transcription regulator which represses the degradation of pyrimidines (rutABCDEFG) and purines (gcl operon) for maintenance of metabolic balance between pyrimidines and purines. It also regulates the synthesis of pyrimidine nucleotides and arginine from glutamine (carAB) and the supply of glutamate (gadABWX).<ref>PMID:16540542</ref> <ref>PMID:17919280</ref> | |
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Escherichia coli K-12]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Almo | + | [[Category: Almo SC]] |
| - | [[Category: Cooper | + | [[Category: Cooper DR]] |
| - | [[Category: Grabowski | + | [[Category: Grabowski M]] |
| - | [[Category: Minor | + | [[Category: Minor W]] |
| - | + | [[Category: Shabalin IG]] | |
| - | [[Category: Shabalin | + | [[Category: Shumilin IA]] |
| - | [[Category: Shumilin | + | |
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Current revision
E. coli transcriptional regulator RUTR with dihydrouracil
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