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4zhx

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Current revision (08:18, 27 September 2023) (edit) (undo)
 
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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4zhx]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZHX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZHX FirstGlance]. <br>
<table><tr><td colspan='2'>[[4zhx]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZHX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZHX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4O7:(5S,6R,7R,9R,13CR,14R,16AS)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,14,15,16,16A-OCTAHYDRO-5H,13CH-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-OL'>4O7</scene>, <scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=C1V:3-[4-(2-HYDROXYPHENYL)PHENYL]-4-OXIDANYL-6-OXIDANYLIDENE-7H-THIENO[2,3-B]PYRIDINE-5-CARBONITRILE'>C1V</scene>, <scene name='pdbligand=C2Z:5-(5-HYDROXYL-ISOXAZOL-3-YL)-FURAN-2-PHOSPHONIC+ACID'>C2Z</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.99&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4O7:(5S,6R,7R,9R,13CR,14R,16AS)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,14,15,16,16A-OCTAHYDRO-5H,13CH-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-OL'>4O7</scene>, <scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=C1V:3-[4-(2-HYDROXYPHENYL)PHENYL]-4-OXIDANYL-6-OXIDANYLIDENE-7H-THIENO[2,3-B]PYRIDINE-5-CARBONITRILE'>C1V</scene>, <scene name='pdbligand=C2Z:5-(5-HYDROXYL-ISOXAZOL-3-YL)-FURAN-2-PHOSPHONIC+ACID'>C2Z</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zhx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zhx OCA], [https://pdbe.org/4zhx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zhx RCSB], [https://www.ebi.ac.uk/pdbsum/4zhx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zhx ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zhx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zhx OCA], [https://pdbe.org/4zhx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zhx RCSB], [https://www.ebi.ac.uk/pdbsum/4zhx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zhx ProSAT]</span></td></tr>
</table>
</table>

Current revision

Novel binding site for allosteric activation of AMPK

PDB ID 4zhx

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