5jwu

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Current revision (09:49, 27 September 2023) (edit) (undo)
 
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<StructureSection load='5jwu' size='340' side='right'caption='[[5jwu]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='5jwu' size='340' side='right'caption='[[5jwu]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5jwu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterobacteria_phage_t4_sensu_lato Enterobacteria phage t4 sensu lato]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JWU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JWU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5jwu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_T4 Escherichia phage T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JWU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JWU FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B20:1,2-DIHYDRO-1,2-AZABORININE'>B20</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[5jwt|5jwt]], [[5jwv|5jwv]], [[5jww|5jww]], [[5jwx|5jwx]], [[5jws|5jws]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B20:1,2-DIHYDRO-1,2-AZABORININE'>B20</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jwu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jwu OCA], [https://pdbe.org/5jwu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jwu RCSB], [https://www.ebi.ac.uk/pdbsum/5jwu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jwu ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jwu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jwu OCA], [https://pdbe.org/5jwu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jwu RCSB], [https://www.ebi.ac.uk/pdbsum/5jwu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jwu ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4]] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>
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[https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Lysin|Lysin]]
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*[[Lysin 3D structures|Lysin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Enterobacteria phage t4 sensu lato]]
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[[Category: Escherichia phage T4]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lysozyme]]
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[[Category: Fischer M]]
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[[Category: Fischer, M]]
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[[Category: Lee H]]
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[[Category: Lee, H]]
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[[Category: Liu S-Y]]
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[[Category: Liu, S Y]]
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[[Category: Shoichet BK]]
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[[Category: Shoichet, B K]]
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[[Category: Hydrolase]]
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[[Category: Phage lysozyme azaborine]]
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Current revision

T4 Lysozyme L99A/M102Q with 1,2-Dihydro-1,2-azaborine Bound

PDB ID 5jwu

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