1n3o

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1n3o.gif|left|200px]]
[[Image:1n3o.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1n3o |SIZE=350|CAPTION= <scene name='initialview01'>1n3o</scene>, resolution 2.0&Aring;
+
The line below this paragraph, containing "STRUCTURE_1n3o", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GYP:METHYL-ALPHA-D-GLUCOPYRANOSIDE'>GYP</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE=
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1n3o| PDB=1n3o | SCENE= }}
-
|RELATEDENTRY=[[1n3p|1N3P]], [[1n3q|1N3Q]]
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1n3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n3o OCA], [http://www.ebi.ac.uk/pdbsum/1n3o PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1n3o RCSB]</span>
+
-
}}
+
'''Pterocarcpus angolensis lectin in complex with alpha-methyl glucose'''
'''Pterocarcpus angolensis lectin in complex with alpha-methyl glucose'''
Line 34: Line 31:
[[Category: Read, J S.]]
[[Category: Read, J S.]]
[[Category: Wyns, L.]]
[[Category: Wyns, L.]]
-
[[Category: carbohydrate recognition]]
+
[[Category: Carbohydrate recognition]]
-
[[Category: glucose]]
+
[[Category: Glucose]]
-
[[Category: lectin]]
+
[[Category: Lectin]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 02:03:00 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:24:58 2008''
+

Revision as of 23:03, 2 May 2008

Image:1n3o.gif

Template:STRUCTURE 1n3o

Pterocarcpus angolensis lectin in complex with alpha-methyl glucose


Overview

The crystal structure of the Man/Glc-specific seed lectin from Pterocarpus angolensis was determined in complex with methyl-alpha-d-glucose, sucrose, and turanose. The carbohydrate binding site contains a classic Man/Glc type specificity loop. Its metal binding loop on the other hand is of the long type, different from what is observed in other Man/Glc-specific legume lectins. Glucose binding in the primary binding site is reminiscent of the glucose complexes of concanavalin A and lentil lectin. Sucrose is found to be bound in a conformation similar as seen in the binding site of lentil lectin. A direct hydrogen bond between Ser-137(OG) to Fru(O2) in Pterocarpus angolensis lectin replaces a water-mediated interaction in the equivalent complex of lentil lectin. In the turanose complex, the binding site of the first molecule in the asymmetric unit contains the alphaGlc1-3betaFruf form of furanose while the second molecule contains the alphaGlc1-3betaFrup form in its binding site.

About this Structure

1N3O is a Single protein structure of sequence from Pterocarpus angolensis. Full crystallographic information is available from OCA.

Reference

Crystal structure of Pterocarpus angolensis lectin in complex with glucose, sucrose, and turanose., Loris R, Imberty A, Beeckmans S, Van Driessche E, Read JS, Bouckaert J, De Greve H, Buts L, Wyns L, J Biol Chem. 2003 May 2;278(18):16297-303. Epub 2003 Feb 19. PMID:12595543 Page seeded by OCA on Sat May 3 02:03:00 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1n3o"
Personal tools