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5k8u
From Proteopedia
(Difference between revisions)
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<StructureSection load='5k8u' size='340' side='right'caption='[[5k8u]], [[Resolution|resolution]] 1.60Å' scene=''> | <StructureSection load='5k8u' size='340' side='right'caption='[[5k8u]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5k8u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[5k8u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Zika_virus Zika virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K8U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5K8U FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.601Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5k8u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k8u OCA], [https://pdbe.org/5k8u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5k8u RCSB], [https://www.ebi.ac.uk/pdbsum/5k8u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5k8u ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5k8u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k8u OCA], [https://pdbe.org/5k8u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5k8u RCSB], [https://www.ebi.ac.uk/pdbsum/5k8u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5k8u ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A146CJG7_ZIKV A0A146CJG7_ZIKV] Peptide 2k: Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[SAAS:SAAS00892720] | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Zika virus]] |
| - | [[Category: Cao | + | [[Category: Cao X]] |
| - | [[Category: Jin | + | [[Category: Jin T]] |
| - | [[Category: Li | + | [[Category: Li Y]] |
| - | + | ||
| - | + | ||
| - | + | ||
Revision as of 10:43, 27 September 2023
Crystal structure of ZIKV NS3 helicase in complex with ADP and Mn2+
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Categories: Large Structures | Zika virus | Cao X | Jin T | Li Y
