5k8u

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<StructureSection load='5k8u' size='340' side='right'caption='[[5k8u]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='5k8u' size='340' side='right'caption='[[5k8u]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5k8u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Zikv Zikv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K8U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5K8U FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5k8u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Zika_virus Zika virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K8U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5K8U FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.601&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[5jwh|5jwh]], [[5k8i|5k8i]], [[5k8l|5k8l]], [[5k8t|5k8t]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5k8u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k8u OCA], [https://pdbe.org/5k8u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5k8u RCSB], [https://www.ebi.ac.uk/pdbsum/5k8u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5k8u ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5k8u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k8u OCA], [https://pdbe.org/5k8u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5k8u RCSB], [https://www.ebi.ac.uk/pdbsum/5k8u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5k8u ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0A146CJG7_ZIKV A0A146CJG7_ZIKV] Peptide 2k: Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[SAAS:SAAS00892720]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Zikv]]
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[[Category: Zika virus]]
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[[Category: Cao, X]]
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[[Category: Cao X]]
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[[Category: Jin, T]]
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[[Category: Jin T]]
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[[Category: Li, Y]]
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[[Category: Li Y]]
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[[Category: Helicase]]
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[[Category: Hydrolase]]
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[[Category: Ntpase]]
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Revision as of 10:43, 27 September 2023

Crystal structure of ZIKV NS3 helicase in complex with ADP and Mn2+

PDB ID 5k8u

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