5kh5

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<StructureSection load='5kh5' size='340' side='right'caption='[[5kh5]], [[Resolution|resolution]] 2.63&Aring;' scene=''>
<StructureSection load='5kh5' size='340' side='right'caption='[[5kh5]], [[Resolution|resolution]] 2.63&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5kh5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Strpn Strpn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KH5 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5KH5 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5kh5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_TIGR4 Streptococcus pneumoniae TIGR4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KH5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KH5 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6TC:~{N}-(3-AZANYL-3-OXIDANYLIDENE-PROPYL)-5-(1-BENZOTHIOPHEN-5-YL)-1-(PHENYLMETHYL)-~{N}-[(4-PROPAN-2-YLOXYPHENYL)METHYL]PYRAZOLE-4-CARBOXAMIDE'>6TC</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.63&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5kh4|5kh4]], [[5kh2|5kh2]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6TC:~{N}-(3-AZANYL-3-OXIDANYLIDENE-PROPYL)-5-(1-BENZOTHIOPHEN-5-YL)-1-(PHENYLMETHYL)-~{N}-[(4-PROPAN-2-YLOXYPHENYL)METHYL]PYRAZOLE-4-CARBOXAMIDE'>6TC</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">uppS, SP_0261 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=170187 STRPN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5kh5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kh5 OCA], [https://pdbe.org/5kh5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5kh5 RCSB], [https://www.ebi.ac.uk/pdbsum/5kh5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5kh5 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5kh5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kh5 OCA], [http://pdbe.org/5kh5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kh5 RCSB], [http://www.ebi.ac.uk/pdbsum/5kh5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kh5 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ISPT_STRPN ISPT_STRPN]] Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
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[https://www.uniprot.org/uniprot/ISPT_STRPN ISPT_STRPN] Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Strpn]]
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[[Category: Streptococcus pneumoniae TIGR4]]
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[[Category: Concha, N O]]
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[[Category: Concha NO]]
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[[Category: Bacterial]]
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[[Category: Native]]
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[[Category: Transferase-transferase inhibitor complex]]
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[[Category: Undecaprenyl s. pneumoniae]]
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[[Category: Upp]]
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Revision as of 10:46, 27 September 2023

Crystal Structure of Steptococcus pneumoniae Undecaprenyl pyrophosphate Synthase (UPPS) IN COMPLEX WITH ~{N}-(3-azanyl-3-oxidanylidene-propyl)-5-(1-benzothiophen-5-yl)-1-(phenylmethyl)-~{N}-[(4-propan-2-yloxyphenyl)methyl]pyrazole-4-carboxamide

PDB ID 5kh5

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