Serine/threonine protein kinase 3D structures
From Proteopedia
(Difference between revisions)
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*'''Pim''' | *'''Pim''' | ||
| - | *Pim1 | + | *Pim1 catalytic domain residues 14-313 |
**[[1xqz]], [[1ywv]], [[4jx3]] – hPim1 catalytic domain <br /> | **[[1xqz]], [[1ywv]], [[4jx3]] – hPim1 catalytic domain <br /> | ||
**[[1yxs]] – hPim1 catalytic domain (mutant) <br /> | **[[1yxs]] – hPim1 catalytic domain (mutant) <br /> | ||
| - | **[[4jx3]] – hPim1 kinase domain <br /> | ||
**[[1xr1]], [[1yxt]] – hPim1 catalytic domain + AMPPNP <br /> | **[[1xr1]], [[1yxt]] – hPim1 catalytic domain + AMPPNP <br /> | ||
**[[1yxu]] – hPim1 catalytic domain + AMP <br /> | **[[1yxu]] – hPim1 catalytic domain + AMP <br /> | ||
| - | **[[1yxv]] | + | **[[1yxv]], [[5ipj]] – hPim1 catalytic domain + quinoline derivative <br /> |
| - | + | ||
**[[1yxx]] – hPim1 catalytic domain + indole derivative <br /> | **[[1yxx]] – hPim1 catalytic domain + indole derivative <br /> | ||
| - | **[[3a99]] – hPim1 kinase domain + phosphoaminophosphonic acid adenylate <br /> | ||
**[[2bzj]], [[2bzh]], [[2bzi]] – hPim1 catalytic domain (mutant) + organometallic ligand <br /> | **[[2bzj]], [[2bzh]], [[2bzi]] – hPim1 catalytic domain (mutant) + organometallic ligand <br /> | ||
| + | **[[2o3p]], [[2o63]], [[2o64]], [[2o65]], [[3c4e]], [[3jxw]], [[3jy0]], [[3jya]], [[3r00]], [[3r01]], [[3r02]], [[3r04]], [[3vbq]], [[3vbt]], [[3vbv]], [[3vbw]], [[3vbx]], [[3vby]], [[3vc4]], [[3umw]], [[3umx]], [[4enx]], [[4eny]], [[4k1b]], [[4k18]], [[4k0y]], [[4iaa]], [[4i41]], [[4ll5]], [[4lm5]], [[4lmu]], [[4mta]], [[4med]], [[4mbl]], [[4mbi]], [[4n6y]], [[4n6z]], [[4n70]], [[4xh6]], [[5iis]], [[5kgd]], [[5kge]], [[5kgg]], [[5kgi]], [[5kgk]], [[5kzi]], [[5vua]], [[5vub]], [[5vuc]], [[6mt0]], [[6vrv]], [[7oov]], [[7oow]], [[7oox]], [[7xsv]] – hPim1 catalytic domain + inhibitor <br /> | ||
| + | **[[2j2i]], [[3we8]] – hPim1 catalytic domain (mutant)+ inhibitor <br /> | ||
| + | |||
| + | *Pim1 kinase domain residues 92-404 | ||
| + | |||
| + | **[[4jx3]] – hPim1 kinase domain <br /> | ||
| + | **[[3uix]], [[5c1q]] – hPim1 kinase domain residues 120-404 + quinoline derivative <br /> | ||
| + | **[[3a99]] – hPim1 kinase domain + phosphoaminophosphonic acid adenylate <br /> | ||
**[[2oi4]], [[3bwf]] – hPim1 kinase domain (mutant) + organometallic ligand <br /> | **[[2oi4]], [[3bwf]] – hPim1 kinase domain (mutant) + organometallic ligand <br /> | ||
| - | **[[1xws]], [[ | + | **[[1xws]], [[4alu]], [[4alv]], [[4alw]], [[4as0]], [[4bzn]], [[4bzo]], [[4dtk]], [[4jx7]], [[4rbl]], [[4rc2]], [[4rc3]], [[4rc4]], [[4ty1]], [[4wrs]], [[4wsy]], [[4wt6]], [[4xhk]], [[[5dgz]], [5dhj]], [[5dia]], [[5dwr]], [[5eol]], [[5kcx]], [[5o11]], [[5o12]], [[5o13]], [[5tel]], [[5tex]], [[5toe]], [[5v80]], [[5v82]]. [[6bsk]], [[6kzi]], [[6l11]], [[6l12]], [[6l13]], [[6l14]], [[6l15]], [[6l16]], [[6l17]], [[6no8]], [[6no9]], [[6vru]], [[6ykd]], [[7zun]] – hPim1 kinase domain + inhibitor <br /> |
**[[6ayd]] – hPim1 kinase domain (mutant)+ inhibitor <br /> | **[[6ayd]] – hPim1 kinase domain (mutant)+ inhibitor <br /> | ||
| - | **[[2o3p]], [[2o63]], [[2o64]], [[2o65]], [[3jxw]], [[3jy0]], [[3jya]], [[3r00]], [[3r01]], [[3r02]], [[3r04]], [[3vbq]], [[3vbt]], [[3vbv]], [[3vbw]], [[3vbx]], [[3vby]], [[3vc4]], [[3umx]], [[4enx]], [[4eny]], [[3umw]], [[4ll5]], [[4lm5]], [[3c4e]], [[5vuc]], [[5vub]], [[5vua]], [[4n70]], [[4n6z]], [[4n6y]], [[4mta]], [[6kzi]], [[4mbl]], [[4mbi]], [[4lmu]], [[4k1b]], [[4k18]], [[4k0y]], [[4iaa]], [[4i41]], [[6mt0]], [[7oov]], [[7oow]], [[7oox]] – hPim1 catalytic domain + inhibitor <br /> | ||
| - | **[[2j2i]], [[3we8]] – hPim1 catalytic domain (mutant)+ inhibitor <br /> | ||
| - | **[[5tur]] - hPim1 + inhibitor <br /> | ||
| - | *Pim1 complex with consensus peptide | + | *Pim1 full length |
| + | |||
| + | **[[4rpv]], [[5tur]] - hPim1 + inhibitor <br /> | ||
| + | |||
| + | *Pim1 complex with consensus peptide (pimtide) | ||
**[[2bil]], [[3cxw]], [[3cy2]], [[3cy3]], [[6qxk]], [[6pcw]], [[6pdi]], [[6pdn]], [[6pdo]], [[6pdp]] – hPim1 kinase domain + inhibitor + consensus peptide<br /> | **[[2bil]], [[3cxw]], [[3cy2]], [[3cy3]], [[6qxk]], [[6pcw]], [[6pdi]], [[6pdn]], [[6pdo]], [[6pdp]] – hPim1 kinase domain + inhibitor + consensus peptide<br /> | ||
**[[3jpv]], [[3qf9]] - hPim1 catalytic domain + inhibitor + consensus peptide<br /> | **[[3jpv]], [[3qf9]] - hPim1 catalytic domain + inhibitor + consensus peptide<br /> | ||
**[[2c3i]], [[5ndt]], [[5n5m]], [[5n5l]], [[5n52]], [[5n51]], [[5n50]], [[5n4z]], [[5n4y]], [[5n4x]], [[5n4v]], [[5n4u]], [[5n4r]], [[5n4o]], [[5n4n]], [[5mzl]] – hPim1 kinase domain (mutant) + inhibitor + consensus peptide <br /> | **[[2c3i]], [[5ndt]], [[5n5m]], [[5n5l]], [[5n52]], [[5n51]], [[5n50]], [[5n4z]], [[5n4y]], [[5n4x]], [[5n4v]], [[5n4u]], [[5n4r]], [[5n4o]], [[5n4n]], [[5mzl]] – hPim1 kinase domain (mutant) + inhibitor + consensus peptide <br /> | ||
| - | **[[4gw8]] – hPim1 catalytic domain (mutant) + inhibitor + | + | **[[4gw8]], [[7qb2]], [[7qfm]], [[7z6u]], [[8afr]] – hPim1 catalytic domain (mutant) + inhibitor + pimtide<br /> |
**[[2bzk]] – hPim1 kinase domain (mutant)+ AMPPNP + consensus peptide <br /> | **[[2bzk]] – hPim1 kinase domain (mutant)+ AMPPNP + consensus peptide <br /> | ||
**[[3ma3]] – hPim1 catalytic domain + inhibitor + PSer + consensus peptide<br /> | **[[3ma3]] – hPim1 catalytic domain + inhibitor + PSer + consensus peptide<br /> | ||
Revision as of 07:59, 1 October 2023
3D structures of serine/threonine protein kinase
Updated on 01-October-2023
