5t3n

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Current revision (12:54, 4 October 2023) (edit) (undo)
 
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<StructureSection load='5t3n' size='340' side='right'caption='[[5t3n]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='5t3n' size='340' side='right'caption='[[5t3n]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5t3n]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plaf7 Plaf7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T3N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T3N FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5t3n]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T3N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5T3N FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=75G:(2S,4AR,6R,7R,7AS)-6-(6-AMINO-2-CHLORO-9H-PURIN-9-YL)-7-HYDROXY-2-SULFANYLTETRAHYDRO-2H,4H-2LAMBDA~5~-FURO[3,2-D][1,3,2]DIOXAPHOSPHININ-2-ONE'>75G</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5kbf|5kbf]], [[5k8s|5k8s]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=75G:(2S,4AR,6R,7R,7AS)-6-(6-AMINO-2-CHLORO-9H-PURIN-9-YL)-7-HYDROXY-2-SULFANYLTETRAHYDRO-2H,4H-2LAMBDA~5~-FURO[3,2-D][1,3,2]DIOXAPHOSPHININ-2-ONE'>75G</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PKAr, PF3D7_1223100, PFL1110c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=36329 PLAF7])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5t3n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t3n OCA], [https://pdbe.org/5t3n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5t3n RCSB], [https://www.ebi.ac.uk/pdbsum/5t3n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5t3n ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/cAMP-dependent_protein_kinase cAMP-dependent protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.11 2.7.11.11] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t3n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t3n OCA], [http://pdbe.org/5t3n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t3n RCSB], [http://www.ebi.ac.uk/pdbsum/5t3n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t3n ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q7KQK0_PLAF7 Q7KQK0_PLAF7]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Plaf7]]
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[[Category: Plasmodium falciparum 3D7]]
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[[Category: CAMP-dependent protein kinase]]
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[[Category: Gilson P]]
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[[Category: Gilson, P]]
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[[Category: Littler DR]]
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[[Category: Littler, D R]]
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[[Category: Camp]]
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[[Category: Cbd]]
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[[Category: Cnb]]
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[[Category: Cyclic adenosine monophosphate]]
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[[Category: Cyclic nucleotide]]
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[[Category: Pkar]]
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[[Category: Plasmodium]]
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[[Category: Protein kinase some]]
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[[Category: Transferase]]
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Current revision

Sp-2Cl-cAMPS bound to PKAR CBD2

PDB ID 5t3n

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OCA

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