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5tcm
From Proteopedia
(Difference between revisions)
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==First Bromodomain from Leishmania donovani LdBPK.091320 complexed with BI-2536== | ==First Bromodomain from Leishmania donovani LdBPK.091320 complexed with BI-2536== | ||
| - | <StructureSection load='5tcm' size='340' side='right' caption='[[5tcm]], [[Resolution|resolution]] 2.20Å' scene=''> | + | <StructureSection load='5tcm' size='340' side='right'caption='[[5tcm]], [[Resolution|resolution]] 2.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5tcm]] is a 3 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5tcm]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_donovani_BPK282A1 Leishmania donovani BPK282A1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TCM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TCM FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=R78:4-{[(7R)-8-CYCLOPENTYL-7-ETHYL-5-METHYL-6-OXO-5,6,7,8-TETRAHYDROPTERIDIN-2-YL]AMINO}-3-METHOXY-N-(1-METHYLPIPERIDIN-4-YL)BENZAMIDE'>R78</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=R78:4-{[(7R)-8-CYCLOPENTYL-7-ETHYL-5-METHYL-6-OXO-5,6,7,8-TETRAHYDROPTERIDIN-2-YL]AMINO}-3-METHOXY-N-(1-METHYLPIPERIDIN-4-YL)BENZAMIDE'>R78</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tcm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tcm OCA], [https://pdbe.org/5tcm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tcm RCSB], [https://www.ebi.ac.uk/pdbsum/5tcm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tcm ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A3Q8I8I6_LEIDO A0A3Q8I8I6_LEIDO] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Arrowsmith | + | [[Category: Leishmania donovani BPK282A1]] |
| - | [[Category: Bountra | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Dong | + | [[Category: Bountra C]] |
| - | [[Category: Edwards | + | [[Category: Dong A]] |
| - | [[Category: Hou | + | [[Category: Edwards AM]] |
| - | [[Category: Hui | + | [[Category: Hou CFD]] |
| - | [[Category: Lin | + | [[Category: Hui R]] |
| - | [[Category: Loppnau | + | [[Category: Lin YH]] |
| - | + | [[Category: Loppnau P]] | |
| - | [[Category: Walker | + | [[Category: Walker JR]] |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
First Bromodomain from Leishmania donovani LdBPK.091320 complexed with BI-2536
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Categories: Large Structures | Leishmania donovani BPK282A1 | Arrowsmith CH | Bountra C | Dong A | Edwards AM | Hou CFD | Hui R | Lin YH | Loppnau P | Walker JR
