5u4n

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Current revision (13:20, 4 October 2023) (edit) (undo)
 
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<StructureSection load='5u4n' size='340' side='right'caption='[[5u4n]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='5u4n' size='340' side='right'caption='[[5u4n]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5u4n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"diplococcus_gonorrhoeae"_(zopf_1885)_lehmann_and_neumann_1896 "diplococcus gonorrhoeae" (zopf 1885) lehmann and neumann 1896]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U4N OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5U4N FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5u4n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_gonorrhoeae Neisseria gonorrhoeae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U4N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5U4N FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fda, WHOF_00031C, WHOF_00393, WHOG_00032C, WHOG_01091, WHOK_00031C, WHOK_01288, WHOL_00032C, WHOL_00481, WHOM_00032C, WHOM_00338, WHON_00032C, WHON_00415, WHOO_00031C, WHOO_00479, WHOP_00030C, WHOP_00448, WHOU_00032C, WHOU_01170, WHOV_00032C, WHOV_01444, WHOW_00031C, WHOW_01140, WHOX_00032C, WHOX_00360, WHOY_00032C, WHOY_00387, WHOZ_00031C, WHOZ_00311 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=485 "Diplococcus gonorrhoeae" (Zopf 1885) Lehmann and Neumann 1896])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fructose-bisphosphate_aldolase Fructose-bisphosphate aldolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.13 4.1.2.13] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5u4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u4n OCA], [https://pdbe.org/5u4n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5u4n RCSB], [https://www.ebi.ac.uk/pdbsum/5u4n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5u4n ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5u4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u4n OCA], [http://pdbe.org/5u4n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5u4n RCSB], [http://www.ebi.ac.uk/pdbsum/5u4n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5u4n ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q5FAI4_NEIG1 Q5FAI4_NEIG1] Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.[ARBA:ARBA00002181][RuleBase:RU365019]
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Fructose-bisphosphate aldolase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Structural genomic]]
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[[Category: Neisseria gonorrhoeae]]
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[[Category: Fructose]]
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[[Category: Lyase]]
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[[Category: Phosphate]]
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[[Category: Ssgcid]]
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Current revision

Crystal structure of a fructose-bisphosphate aldolase from Neisseria gonorrhoeae

PDB ID 5u4n

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