This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5u6a

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:21, 4 October 2023) (edit) (undo)
 
Line 1: Line 1:
==CRYSTAL STRUCTURE OF I83E MEDITOPE-ENABLED TRASTUZUMAB WITH AZIDO-PEG3-MEDITOPE==
==CRYSTAL STRUCTURE OF I83E MEDITOPE-ENABLED TRASTUZUMAB WITH AZIDO-PEG3-MEDITOPE==
-
<StructureSection load='5u6a' size='340' side='right' caption='[[5u6a]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
+
<StructureSection load='5u6a' size='340' side='right'caption='[[5u6a]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5u6a]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/"diplococcus_magnus"_prevot_1933 "diplococcus magnus" prevot 1933], [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U6A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5U6A FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5u6a]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Finegoldia_magna Finegoldia magna], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U6A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5U6A FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MRY:MESO-ERYTHRITOL'>MRY</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.736&#8491;</td></tr>
-
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=2GX:BETA-PHENYL-L-PHENYLALANINE'>2GX</scene>, <scene name='pdbligand=562:'>562</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2GX:BETA-PHENYL-L-PHENYLALANINE'>2GX</scene>, <scene name='pdbligand=562:N~5~-[N-(2-{2-[2-(triaza-1,2-dien-2-ium-1-yl)ethoxy]ethoxy}ethyl)carbamimidoyl]-L-ornithine'>562</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=MRY:MESO-ERYTHRITOL'>MRY</scene></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5u3d|5u3d]], [[5u5f|5u5f]], [[5u5m|5u5m]]</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5u6a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u6a OCA], [https://pdbe.org/5u6a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5u6a RCSB], [https://www.ebi.ac.uk/pdbsum/5u6a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5u6a ProSAT]</span></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">spa ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5u6a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u6a OCA], [http://pdbe.org/5u6a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5u6a RCSB], [http://www.ebi.ac.uk/pdbsum/5u6a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5u6a ProSAT]</span></td></tr>
+
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/Q51918_FINMA Q51918_FINMA]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Diplococcus magnus prevot 1933]]
+
[[Category: Finegoldia magna]]
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
-
[[Category: Avery, K A]]
+
[[Category: Large Structures]]
-
[[Category: Bzymek, K P]]
+
[[Category: Staphylococcus aureus]]
-
[[Category: Horne, D]]
+
[[Category: Synthetic construct]]
-
[[Category: Ma, Y]]
+
[[Category: Avery KA]]
-
[[Category: Pucket, J]]
+
[[Category: Bzymek KP]]
-
[[Category: Williams, J C]]
+
[[Category: Horne D]]
-
[[Category: Xie, J]]
+
[[Category: Ma Y]]
-
[[Category: Zer, C]]
+
[[Category: Pucket J]]
-
[[Category: Antibody]]
+
[[Category: Williams JC]]
-
[[Category: Antibody-drug conjugate]]
+
[[Category: Xie J]]
-
[[Category: Immune system]]
+
[[Category: Zer C]]

Current revision

CRYSTAL STRUCTURE OF I83E MEDITOPE-ENABLED TRASTUZUMAB WITH AZIDO-PEG3-MEDITOPE

PDB ID 5u6a

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools