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5uai

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Current revision (13:24, 4 October 2023) (edit) (undo)
 
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<StructureSection load='5uai' size='340' side='right'caption='[[5uai]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
<StructureSection load='5uai' size='340' side='right'caption='[[5uai]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5uai]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UAI OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5UAI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5uai]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UAI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UAI FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fmt, PA0018 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionyl-tRNA_formyltransferase Methionyl-tRNA formyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.2.9 2.1.2.9] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5uai FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uai OCA], [https://pdbe.org/5uai PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5uai RCSB], [https://www.ebi.ac.uk/pdbsum/5uai PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5uai ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5uai FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uai OCA], [http://pdbe.org/5uai PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uai RCSB], [http://www.ebi.ac.uk/pdbsum/5uai PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uai ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/FMT_PSEAE FMT_PSEAE]] Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by: (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity).
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[https://www.uniprot.org/uniprot/FMT_PSEAE FMT_PSEAE] Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by: (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Methionyl-tRNA formyltransferase]]
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[[Category: Pseudomonas aeruginosa PAO1]]
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[[Category: Pseae]]
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[[Category: Structural genomic]]
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[[Category: Fmt]]
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[[Category: Methionyl-trna formyltransferase]]
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[[Category: Ssgcid]]
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[[Category: Transferase]]
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Current revision

Crystal structure of Methionyl-tRNA formyltransferase from Pseudomonas aeruginosa

PDB ID 5uai

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