1n6z

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[[Image:1n6z.gif|left|200px]]
[[Image:1n6z.gif|left|200px]]
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{{Structure
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|PDB= 1n6z |SIZE=350|CAPTION= <scene name='initialview01'>1n6z</scene>
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The line below this paragraph, containing "STRUCTURE_1n6z", creates the "Structure Box" on the page.
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|GENE= YML108W OR YM8339.11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam08987 DUF1892]</span>
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{{STRUCTURE_1n6z| PDB=1n6z | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1n6z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n6z OCA], [http://www.ebi.ac.uk/pdbsum/1n6z PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1n6z RCSB]</span>
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'''Solution NMR Structure of Protein YML108W from Saccharomyces cerevisiae. A novel member of the split bab fold. Northeast Structural Genomics Consortium Target YT601.'''
'''Solution NMR Structure of Protein YML108W from Saccharomyces cerevisiae. A novel member of the split bab fold. Northeast Structural Genomics Consortium Target YT601.'''
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: northeast structural genomics consortium]]
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[[Category: Northeast structural genomics consortium]]
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[[Category: protein structure initiative]]
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[[Category: structural genomic]]
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Revision as of 23:10, 2 May 2008

Template:STRUCTURE 1n6z

Solution NMR Structure of Protein YML108W from Saccharomyces cerevisiae. A novel member of the split bab fold. Northeast Structural Genomics Consortium Target YT601.


Overview

As part of the Northeast Structural Genomics Consortium pilot project focused on small eukaryotic proteins and protein domains, we have determined the NMR structure of the protein encoded by ORF YML108W from Saccharomyces cerevisiae. YML108W belongs to one of the numerous structural proteomics targets whose biological function is unknown. Moreover, this protein does not have sequence similarity to any other protein. The NMR structure of YML108W consists of a four-stranded beta-sheet with strand order 2143 and two alpha-helices, with an overall topology of betabetaalphabetabetaalpha. Strand beta1 runs parallel to beta4, and beta2:beta1 and beta4:beta3 pairs are arranged in an antiparallel fashion. Although this fold belongs to the split betaalphabeta family, it appears to be unique among this family; it is a novel arrangement of secondary structure, thereby expanding the universe of protein folds.

About this Structure

1N6Z is a Single protein structure of sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

A novel member of the split betaalphabeta fold: Solution structure of the hypothetical protein YML108W from Saccharomyces cerevisiae., Pineda-Lucena A, Liao JC, Cort JR, Yee A, Kennedy MA, Edwards AM, Arrowsmith CH, Protein Sci. 2003 May;12(5):1136-40. PMID:12717036 Page seeded by OCA on Sat May 3 02:10:23 2008

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