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5v0u
From Proteopedia
(Difference between revisions)
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<StructureSection load='5v0u' size='340' side='right'caption='[[5v0u]], [[Resolution|resolution]] 2.45Å' scene=''> | <StructureSection load='5v0u' size='340' side='right'caption='[[5v0u]], [[Resolution|resolution]] 2.45Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5v0u]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5v0u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/Wilson-Smith/1933(H1N1)) Influenza A virus (A/Wilson-Smith/1933(H1N1))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V0U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5V0U FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8QG:4-(5-CHLOROTHIOPHEN-2-YL)-1H-PYRAZOLE'>8QG</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5v0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v0u OCA], [https://pdbe.org/5v0u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5v0u RCSB], [https://www.ebi.ac.uk/pdbsum/5v0u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5v0u ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/PA_I33A0 PA_I33A0] Implicated in endonuclease cleavage of capped RNA primers. Displays an elongation factor activity in viral RNA synthesis. Dispensable for viral transcription, but not replication. |
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: I33a0]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Structural genomic]] | ||
| - | [[Category: Fbld]] | ||
| - | [[Category: Flu]] | ||
| - | [[Category: Fragment screening]] | ||
| - | [[Category: Fragment-based ligand discovery]] | ||
| - | [[Category: Ppi]] | ||
| - | [[Category: Protein-protein interface]] | ||
| - | [[Category: Ssgcid]] | ||
| - | [[Category: Transcription]] | ||
Current revision
Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to follow on fragment EBSI-4723 4-(5-chlorothiophen-2-yl)-1H-pyrazole
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