1n7a

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[[Image:1n7a.gif|left|200px]]
[[Image:1n7a.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 1n7a |SIZE=350|CAPTION= <scene name='initialview01'>1n7a</scene>, resolution 1.20&Aring;
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The line below this paragraph, containing "STRUCTURE_1n7a", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=A:ADENOSINE-5&#39;-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=BGM:8-BROMO-2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>BGM</scene>, <scene name='pdbligand=G:GUANOSINE-5&#39;-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene>, <scene name='pdbligand=U:URIDINE-5&#39;-MONOPHOSPHATE'>U</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY=
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or leave the SCENE parameter empty for the default display.
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|GENE=
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-->
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|DOMAIN=
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{{STRUCTURE_1n7a| PDB=1n7a | SCENE= }}
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|RELATEDENTRY=[[1n7b|1N7B]], [[1n6x|1N6X]], [[1n6y|1N6Y]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1n7a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n7a OCA], [http://www.ebi.ac.uk/pdbsum/1n7a PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1n7a RCSB]</span>
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}}
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'''RIP-Radiation-damage Induced Phasing'''
'''RIP-Radiation-damage Induced Phasing'''
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==About this Structure==
==About this Structure==
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1N7A is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N7A OCA].
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N7A OCA].
==Reference==
==Reference==
Specific radiation damage can be used to solve macromolecular crystal structures., Ravelli RB, Leiros HK, Pan B, Caffrey M, McSweeney S, Structure. 2003 Feb;11(2):217-24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12575941 12575941]
Specific radiation damage can be used to solve macromolecular crystal structures., Ravelli RB, Leiros HK, Pan B, Caffrey M, McSweeney S, Structure. 2003 Feb;11(2):217-24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12575941 12575941]
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[[Category: Protein complex]]
 
[[Category: Caffrey, M.]]
[[Category: Caffrey, M.]]
[[Category: Leiros, H K.S.]]
[[Category: Leiros, H K.S.]]
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[[Category: Pan, B.]]
[[Category: Pan, B.]]
[[Category: Ravelli, R B.G.]]
[[Category: Ravelli, R B.G.]]
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[[Category: dna]]
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[[Category: Dna]]
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[[Category: rna]]
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[[Category: Rna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 02:11:01 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:26:23 2008''
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Revision as of 23:11, 2 May 2008

Image:1n7a.gif

Template:STRUCTURE 1n7a

RIP-Radiation-damage Induced Phasing


Overview

The use of third generation synchrotron sources has led to renewed concern about the effect of ionizing radiation on crystalline biological samples. In general, the problem is seen as one to be avoided. However, in this paper, it is shown that, far from being a hindrance to successful structure determination, radiation damage provides an opportunity for phasing macromolecular structures. This is successfully demonstrated for both a protein and an oligonucleotide, by way of which complete models were built automatically. The possibility that, through the exploitation of radiation damage, the phase problem could become less of a barrier to macromolecular crystal structure determination is discussed.

About this Structure

Full crystallographic information is available from OCA.

Reference

Specific radiation damage can be used to solve macromolecular crystal structures., Ravelli RB, Leiros HK, Pan B, Caffrey M, McSweeney S, Structure. 2003 Feb;11(2):217-24. PMID:12575941 Page seeded by OCA on Sat May 3 02:11:01 2008

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