5v6r

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Current revision (13:42, 4 October 2023) (edit) (undo)
 
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<StructureSection load='5v6r' size='340' side='right'caption='[[5v6r]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='5v6r' size='340' side='right'caption='[[5v6r]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5v6r]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V6R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5V6R FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5v6r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V6R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5V6R FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5v6b|5v6b]], [[5v6e|5v6e]], [[5v6h|5v6h]], [[5v6t|5v6t]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Plxnd1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5v6r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v6r OCA], [https://pdbe.org/5v6r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5v6r RCSB], [https://www.ebi.ac.uk/pdbsum/5v6r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5v6r ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5v6r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v6r OCA], [http://pdbe.org/5v6r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v6r RCSB], [http://www.ebi.ac.uk/pdbsum/5v6r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v6r ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PLXD1_MOUSE PLXD1_MOUSE]] Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Mediates anti-angiogenic signaling in response to SEMA3E. Required for normal development of the heart and vasculature.<ref>PMID:15239958</ref> <ref>PMID:17318185</ref> <ref>PMID:18992737</ref> <ref>PMID:19027330</ref> <ref>PMID:19421194</ref> <ref>PMID:22179111</ref>
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[https://www.uniprot.org/uniprot/PLXD1_MOUSE PLXD1_MOUSE] Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Mediates anti-angiogenic signaling in response to SEMA3E. Required for normal development of the heart and vasculature.<ref>PMID:15239958</ref> <ref>PMID:17318185</ref> <ref>PMID:18992737</ref> <ref>PMID:19027330</ref> <ref>PMID:19421194</ref> <ref>PMID:22179111</ref>
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Plexin|Plexin]]
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*[[Plexin 3D structures|Plexin 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Shang, G]]
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[[Category: Shang G]]
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[[Category: Zhang, X]]
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[[Category: Zhang X]]
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[[Category: Protein binding]]
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[[Category: Rap gap]]
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Current revision

Structure of Plexin D1 intracellular domain

PDB ID 5v6r

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