This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5vei

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:47, 4 October 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='5vei' size='340' side='right'caption='[[5vei]], [[Resolution|resolution]] 1.33&Aring;' scene=''>
<StructureSection load='5vei' size='340' side='right'caption='[[5vei]], [[Resolution|resolution]] 1.33&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5vei]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4igz 4igz]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VEI OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5VEI FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5vei]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4igz 4igz]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VEI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5VEI FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.33&#8491;</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5vei FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vei OCA], [http://pdbe.org/5vei PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vei RCSB], [http://www.ebi.ac.uk/pdbsum/5vei PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vei ProSAT]</span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5vei FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vei OCA], [https://pdbe.org/5vei PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5vei RCSB], [https://www.ebi.ac.uk/pdbsum/5vei PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5vei ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/SRBS2_HUMAN SRBS2_HUMAN] Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.<ref>PMID:9211900</ref> <ref>PMID:12475393</ref>
 +
== References ==
 +
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
 +
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Arrowsmith, C H]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Bountra, C]]
+
[[Category: Bountra C]]
-
[[Category: Edwards, A M]]
+
[[Category: Edwards AM]]
-
[[Category: Gu, J]]
+
[[Category: Gu J]]
-
[[Category: Huang, H]]
+
[[Category: Huang H]]
-
[[Category: Liu, K]]
+
[[Category: Liu K]]
-
[[Category: Liu, Y]]
+
[[Category: Liu Y]]
-
[[Category: Min, J]]
+
[[Category: Min J]]
-
[[Category: Structural genomic]]
+
[[Category: Sidhu SS]]
-
[[Category: Sidhu, S S]]
+
[[Category: Tempel W]]
-
[[Category: Tempel, W]]
+
-
[[Category: Protein binding]]
+
-
[[Category: Sgc]]
+
-
[[Category: Sh3]]
+
-
[[Category: Src homology 3 domain]]
+

Current revision

Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2

PDB ID 5vei

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5vei"
Personal tools