5vpl

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Current revision (13:54, 4 October 2023) (edit) (undo)
 
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<StructureSection load='5vpl' size='340' side='right'caption='[[5vpl]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='5vpl' size='340' side='right'caption='[[5vpl]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5vpl]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Dermatophagoides_farinae Dermatophagoides farinae] and [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3rvv 3rvv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VPL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5VPL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5vpl]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Dermatophagoides_farinae Dermatophagoides farinae] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3rvv 3rvv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VPL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5VPL FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[5vpg|5vpg]], [[5vph|5vph]], [[5vpk|5vpk]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5vpl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vpl OCA], [https://pdbe.org/5vpl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5vpl RCSB], [https://www.ebi.ac.uk/pdbsum/5vpl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5vpl ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5vpl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vpl OCA], [https://pdbe.org/5vpl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5vpl RCSB], [https://www.ebi.ac.uk/pdbsum/5vpl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5vpl ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PEPT1_DERFA PEPT1_DERFA] Thiol protease that hydrolyzes proteins, with a preference for Phe or basic residues.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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[[Category: Dermatophagoides farinae]]
[[Category: Dermatophagoides farinae]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Chapman, M D]]
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[[Category: Chapman MD]]
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[[Category: Chruszcz, M]]
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[[Category: Chruszcz M]]
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[[Category: Minor, W]]
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[[Category: Minor W]]
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[[Category: Pomes, A]]
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[[Category: Pomes A]]
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[[Category: Vailes, L D]]
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[[Category: Vailes LD]]
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[[Category: Complex between an allergen and fab fragment of 4c1 antibody]]
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[[Category: Hydrolase-immune system complex]]
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Current revision

CRYSTAL STRUCTURE OF DER F 1 COMPLEXED WITH FAB 4C1

PDB ID 5vpl

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Proteopedia Page Contributors and Editors (what is this?)

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