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5w70

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Current revision (14:08, 4 October 2023) (edit) (undo)
 
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<StructureSection load='5w70' size='340' side='right'caption='[[5w70]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='5w70' size='340' side='right'caption='[[5w70]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5w70]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"streptomyces_ribosidificus"_shomura_and_niida "streptomyces ribosidificus" shomura and niida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5W70 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5W70 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5w70]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_ribosidificus Streptomyces ribosidificus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5W70 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5W70 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9YM:[4-({[(1R,2S,3S,4R,5S)-5-amino-2,3,4-trihydroxycyclohexyl]amino}methyl)-5-hydroxy-6-methylpyridin-3-yl]methyl+dihydrogen+phosphate'>9YM</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rbmB, rbcS, ribS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=80859 "Streptomyces ribosidificus" Shomura and Niida])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9YM:[4-({[(1R,2S,3S,4R,5S)-5-amino-2,3,4-trihydroxycyclohexyl]amino}methyl)-5-hydroxy-6-methylpyridin-3-yl]methyl+dihydrogen+phosphate'>9YM</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5w70 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5w70 OCA], [http://pdbe.org/5w70 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5w70 RCSB], [http://www.ebi.ac.uk/pdbsum/5w70 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5w70 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5w70 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5w70 OCA], [https://pdbe.org/5w70 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5w70 RCSB], [https://www.ebi.ac.uk/pdbsum/5w70 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5w70 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/GLDSA_STRRI GLDSA_STRRI]] Catalyzes the PLP-dependent transamination of 2-deoxy-scyllo-inosose (2-DOI) to form 2-deoxy-scyllo-inosamine (2-DOIA) using L-glutamine as the amino donor. Also catalyzes the transamination of 3-amino-2,3-dideoxy-scyllo-inosose (keto-2-DOIA) into 2-deoxystreptamine (2-DOS).[UniProtKB:Q6L739]
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[https://www.uniprot.org/uniprot/GLDSA_STRRI GLDSA_STRRI] Catalyzes the PLP-dependent transamination of 2-deoxy-scyllo-inosose (2-DOI) to form 2-deoxy-scyllo-inosamine (2-DOIA) using L-glutamine as the amino donor. Also catalyzes the transamination of 3-amino-2,3-dideoxy-scyllo-inosose (keto-2-DOIA) into 2-deoxystreptamine (2-DOS).[UniProtKB:Q6L739]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Streptomyces ribosidificus shomura and niida]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Holden, H M]]
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[[Category: Streptomyces ribosidificus]]
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[[Category: Thoden, J B]]
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[[Category: Holden HM]]
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[[Category: Zachman-Brockmeyer, T R]]
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[[Category: Thoden JB]]
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[[Category: Aminocyclitol antibiotic]]
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[[Category: Zachman-Brockmeyer TR]]
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[[Category: Aminoglycoside]]
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[[Category: Aminotransferase]]
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[[Category: Ribostamycin]]
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[[Category: Transferase]]
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Current revision

X-ray Structure of RbmB from Streptomyces ribosidificus

PDB ID 5w70

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