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5wk3

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Current revision (14:15, 4 October 2023) (edit) (undo)
 
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==CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CCL17 AND M116 FAB==
==CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CCL17 AND M116 FAB==
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<StructureSection load='5wk3' size='340' side='right' caption='[[5wk3]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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<StructureSection load='5wk3' size='340' side='right'caption='[[5wk3]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5wk3]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WK3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WK3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5wk3]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WK3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5WK3 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CCL17, SCYA17, TARC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wk3 OCA], [http://pdbe.org/5wk3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wk3 RCSB], [http://www.ebi.ac.uk/pdbsum/5wk3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wk3 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5wk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wk3 OCA], [https://pdbe.org/5wk3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5wk3 RCSB], [https://www.ebi.ac.uk/pdbsum/5wk3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5wk3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CCL17_HUMAN CCL17_HUMAN]] Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4.<ref>PMID:10540332</ref>
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[https://www.uniprot.org/uniprot/CCL17_HUMAN CCL17_HUMAN] Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4.<ref>PMID:10540332</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Gilliland, G L]]
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[[Category: Large Structures]]
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[[Category: Obmolova, G]]
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[[Category: Gilliland GL]]
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[[Category: Teplyakov, A]]
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[[Category: Obmolova G]]
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[[Category: Immune system]]
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[[Category: Teplyakov A]]

Current revision

CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CCL17 AND M116 FAB

PDB ID 5wk3

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