6aoi

<table><tr><td colspan='2'>[[6aoi]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AOI OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6AOI FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BOJ:5-(4-phenylpiperazin-1-yl)-6-propylpyrimidine-2,4-diamine'>BOJ</scene>, <scene name='pdbligand=CB3:10-PROPARGYL-5,8-DIDEAZAFOLIC+ACID'>CB3</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr>

<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6aog|6aog]]</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6aoi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6aoi OCA], [http://pdbe.org/6aoi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6aoi RCSB], [http://www.ebi.ac.uk/pdbsum/6aoi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6aoi ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/DRTS_TOXGO DRTS_TOXGO]] Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity).

[[Category: Chen, Z]]

[[Category: Li, Y]]

[[Category: Lu, H]]

[[Category: Thomas, S B]]

[[Category: Dhfr]]

[[Category: Oxidoreductase]]

[[Category: Pyrimethamine]]