6bc7

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==Cryo X-ray structure of sisomicin bound AAC-VIa==
==Cryo X-ray structure of sisomicin bound AAC-VIa==
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<StructureSection load='6bc7' size='340' side='right' caption='[[6bc7]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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<StructureSection load='6bc7' size='340' side='right'caption='[[6bc7]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6bc7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"aerobacter_cloacae"_(jordan_1890)_bergey_et_al._1923 "aerobacter cloacae" (jordan 1890) bergey et al. 1923]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BC7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BC7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6bc7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterobacter_cloacae Enterobacter cloacae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BC7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BC7 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=SIS:(1S,2S,3R,4S,6R)-4,6-DIAMINO-3-{[(2S,3R)-3-AMINO-6-(AMINOMETHYL)-3,4-DIHYDRO-2H-PYRAN-2-YL]OXY}-2-HYDROXYCYCLOHEXYL+3-DEOXY-4-C-METHYL-3-(METHYLAMINO)-BETA-L-ARABINOPYRANOSIDE'>SIS</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aac 3-VI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=550 "Aerobacter cloacae" (Jordan 1890) Bergey et al. 1923])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=SIS:(1S,2S,3R,4S,6R)-4,6-DIAMINO-3-{[(2S,3R)-3-AMINO-6-(AMINOMETHYL)-3,4-DIHYDRO-2H-PYRAN-2-YL]OXY}-2-HYDROXYCYCLOHEXYL+3-DEOXY-4-C-METHYL-3-(METHYLAMINO)-BETA-L-ARABINOPYRANOSIDE'>SIS</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bc7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bc7 OCA], [http://pdbe.org/6bc7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bc7 RCSB], [http://www.ebi.ac.uk/pdbsum/6bc7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bc7 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bc7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bc7 OCA], [https://pdbe.org/6bc7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bc7 RCSB], [https://www.ebi.ac.uk/pdbsum/6bc7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bc7 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q47030_ENTCL Q47030_ENTCL]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Cuneo, M J]]
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[[Category: Enterobacter cloacae]]
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[[Category: Kumar, P]]
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[[Category: Large Structures]]
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[[Category: Acetyltransferase]]
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[[Category: Cuneo MJ]]
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[[Category: Sisomicin]]
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[[Category: Kumar P]]
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[[Category: Transferase-antibiotic complex]]
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Cryo X-ray structure of sisomicin bound AAC-VIa

PDB ID 6bc7

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