6cj9
From Proteopedia
(Difference between revisions)
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<StructureSection load='6cj9' size='340' side='right'caption='[[6cj9]], [[Resolution|resolution]] 1.70Å' scene=''> | <StructureSection load='6cj9' size='340' side='right'caption='[[6cj9]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6cj9]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[6cj9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dioclea_lasiophylla Dioclea lasiophylla]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=5u37 5u37]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CJ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CJ9 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=XMM:(2R,3S,4S,5S,6R)-2-(5-BROMO-4-CHLORO-1H-INDOL-3-YLOXY)-TETRAHYDRO-6-(HYDROXYMETHYL)-2H-PYRAN-3,4,5-TRIOL'>XMM</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=XMM:(2R,3S,4S,5S,6R)-2-(5-BROMO-4-CHLORO-1H-INDOL-3-YLOXY)-TETRAHYDRO-6-(HYDROXYMETHYL)-2H-PYRAN-3,4,5-TRIOL'>XMM</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6cj9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cj9 OCA], [https://pdbe.org/6cj9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6cj9 RCSB], [https://www.ebi.ac.uk/pdbsum/6cj9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6cj9 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/LECA_DIOLA LECA_DIOLA] D-mannose-binding lectin that also binds alpha-methyl-D-mannoside with even higher affinity (PubMed:24008245). Has hemagglutinating activity against rabbit erythrocytes (PubMed:24008245). Shows toxicity against the brine shrimp A.nauplii (PubMed:24008245). Induces reversible paw edema and hypernociceptivity in rats (PubMed:28196677).<ref>PMID:24008245</ref> <ref>PMID:28196677</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Dioclea lasiophylla]] | [[Category: Dioclea lasiophylla]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Araripe | + | [[Category: Araripe DA]] |
| - | [[Category: Cavada | + | [[Category: Cavada BS]] |
| - | [[Category: Leal | + | [[Category: Leal RB]] |
| - | [[Category: Nascimento | + | [[Category: Nascimento KS]] |
| - | [[Category: Neco | + | [[Category: Neco AHB]] |
| - | [[Category: Osterne | + | [[Category: Osterne VJS]] |
| - | [[Category: Pinto-Junior | + | [[Category: Pinto-Junior VR]] |
| - | [[Category: Rocha | + | [[Category: Rocha CRC]] |
| - | [[Category: Santiago | + | [[Category: Santiago MQ]] |
| - | [[Category: Silva-Filho | + | [[Category: Silva-Filho JC]] |
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Current revision
Crystal structure of lectin from Dioclea lasiophylla seeds (DlyL) complexed with X-Man
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