6ck7

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<StructureSection load='6ck7' size='340' side='right'caption='[[6ck7]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='6ck7' size='340' side='right'caption='[[6ck7]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6ck7]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CK7 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6CK7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6ck7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Legionella_pneumophila Legionella pneumophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CK7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CK7 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BB2:ACTINONIN'>BB2</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6caz|6caz]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BB2:ACTINONIN'>BB2</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide_deformylase Peptide deformylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.88 3.5.1.88] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ck7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ck7 OCA], [https://pdbe.org/6ck7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ck7 RCSB], [https://www.ebi.ac.uk/pdbsum/6ck7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ck7 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6ck7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ck7 OCA], [http://pdbe.org/6ck7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ck7 RCSB], [http://www.ebi.ac.uk/pdbsum/6ck7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ck7 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/A0A128NM93_LEGPN A0A128NM93_LEGPN]] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.[HAMAP-Rule:MF_00163]
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[https://www.uniprot.org/uniprot/Q5ZSC4_LEGPH Q5ZSC4_LEGPH] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.[HAMAP-Rule:MF_00163]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Peptide deformylase]]
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[[Category: Legionella pneumophila]]
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[[Category: Structural genomic]]
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[[Category: Formate]]
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[[Category: Formyl-l-methionyl peptide]]
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[[Category: Hydrolase-antibiotic complex]]
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[[Category: Legionnaires' disease]]
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[[Category: Methionyl peptide]]
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[[Category: National institute of allergy and infectious disease]]
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[[Category: Niaid]]
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[[Category: Ssgcid]]
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Revision as of 15:06, 4 October 2023

Crystal structure of a peptide deformylase from Legionella pneumophila bound to actinonin

PDB ID 6ck7

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