6cxw

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Current revision (15:13, 4 October 2023) (edit) (undo)
 
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<StructureSection load='6cxw' size='340' side='right'caption='[[6cxw]], [[Resolution|resolution]] 1.83&Aring;' scene=''>
<StructureSection load='6cxw' size='340' side='right'caption='[[6cxw]], [[Resolution|resolution]] 1.83&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6cxw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CXW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CXW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6cxw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CXW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CXW FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wee|4wee]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.832&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Syt1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6cxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cxw OCA], [https://pdbe.org/6cxw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6cxw RCSB], [https://www.ebi.ac.uk/pdbsum/6cxw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6cxw ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cxw OCA], [http://pdbe.org/6cxw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cxw RCSB], [http://www.ebi.ac.uk/pdbsum/6cxw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cxw ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SYT1_RAT SYT1_RAT]] May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.
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[https://www.uniprot.org/uniprot/SYT1_RAT SYT1_RAT] May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.
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==See Also==
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*[[Synaptotagmin 3D structures|Synaptotagmin 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Buffalo rat]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Sutton, R B]]
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[[Category: Rattus norvegicus]]
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[[Category: C2 domain]]
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[[Category: Sutton RB]]
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[[Category: Exocytosis]]
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Current revision

Synaptotagmin 1 C2A beta4 chimera with enhanced PIP2 binding function

PDB ID 6cxw

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