3au9

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<StructureSection load='3au9' size='340' side='right'caption='[[3au9]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3au9' size='340' side='right'caption='[[3au9]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3au9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plafa Plafa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AU9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AU9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3au9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AU9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AU9 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FOM:3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC+ACID'>FOM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3au8|3au8]], [[3aua|3aua]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FOM:3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC+ACID'>FOM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dxr ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 PLAFA])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3au9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3au9 OCA], [https://pdbe.org/3au9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3au9 RCSB], [https://www.ebi.ac.uk/pdbsum/3au9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3au9 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3au9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3au9 OCA], [https://pdbe.org/3au9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3au9 RCSB], [https://www.ebi.ac.uk/pdbsum/3au9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3au9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/DXR_PLAFX DXR_PLAFX]] Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).<ref>PMID:10477522</ref>
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[https://www.uniprot.org/uniprot/DXR_PLAFX DXR_PLAFX] Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).<ref>PMID:10477522</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[DXP reductoisomerase|DXP reductoisomerase]]
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*[[DXP reductoisomerase 3D Structures|DXP reductoisomerase 3D Structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Plafa]]
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[[Category: Plasmodium falciparum]]
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[[Category: Kitade, Y]]
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[[Category: Kitade Y]]
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[[Category: Kusakabe, Y]]
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[[Category: Kusakabe Y]]
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[[Category: Nakamura, K T]]
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[[Category: Nakamura KT]]
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[[Category: Nakanishi, M]]
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[[Category: Nakanishi M]]
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[[Category: Tanaka, N]]
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[[Category: Tanaka N]]
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[[Category: Umeda, T]]
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[[Category: Umeda T]]
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[[Category: Isomerase-isomerase inhibitor complex]]
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[[Category: Nadph binding]]
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Revision as of 15:56, 4 October 2023

Crystal structure of the quaternary complex-1 of an isomerase

PDB ID 3au9

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