Ras GTPase activating protein

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*RasGAP 1
*RasGAP 1
-
**[[2gqi]], [[2m51]] – hRasGAP SH3 domain – human – NMR<br />
+
**[[2gqi]] – hRasGAP SH3 domain 281-341 – human – NMR<br />
-
**[[2j05]], [[2j06]], [[4fss]] - hRasGAP SH3 domain<br />
+
**[[2j05]], [[2j06]], [[4fss]] - hRasGAP SH3 domain<br />
 +
**[[2m51]] – hRasGAP SH3 domain 58-118 + DLC1 RhoGAP domain 671-880<br />
 +
**[[2gsb]], [[6wax]] - hRasGAP C-terminal SH2 domain 341-446 – NMR<br />
 +
**[[6pxb]] - hRasGAP N-terminal SH2 domain 174-280<br />
 +
**[[6pxc]] - hRasGAP N-terminal SH2 domain + RhoGAP peptide<br />
 +
**[[6way]] - hRasGAP C-terminal SH2 domain + RhoGAP peptide<br />
 +
**[[8dgq]] - hRasGAP 174-444 + RhoGAP peptide<br />
**[[6wax]] - hRasGAP C-terminal SH2 domain<br />
**[[6wax]] - hRasGAP C-terminal SH2 domain<br />
-
**[[6way]] - hRasGAP C-terminal SH2 domain + p190RasGAP peptide<br />
 
-
**[[6pxb]] - hRasGAP N-terminal SH2 domain<br />
 
-
**[[6pxc]] - hRasGAP N-terminal SH2 domain + p190RasGAP peptide<br />
 
**[[2gsb]] - hRasGAP SH2 domain – NMR<br />
**[[2gsb]] - hRasGAP SH2 domain – NMR<br />
**[[1wer]] - hRasGAP catalytic domain 714-1047<br />
**[[1wer]] - hRasGAP catalytic domain 714-1047<br />

Revision as of 08:49, 8 October 2023

Human Ras GTPase activating protein dimer SH3 domain (PDB code 2j05).

Drag the structure with the mouse to rotate

3D Structures of Ras GTPase activating protein

Updated on 08-October-2023

References

  1. Tocque B, Delumeau I, Parker F, Maurier F, Multon MC, Schweighoffer F. Ras-GTPase activating protein (GAP): a putative effector for Ras. Cell Signal. 1997 Feb;9(2):153-8. PMID:9113414
  2. Maertens O, Cichowski K. An expanding role for RAS GTPase activating proteins (RAS GAPs) in cancer. Adv Biol Regul. 2014 May;55:1-14. doi: 10.1016/j.jbior.2014.04.002. Epub 2014 Apr, 30. PMID:24814062 doi:http://dx.doi.org/10.1016/j.jbior.2014.04.002
  3. Harata K, Kubo Y. Ras GTPase activating protein CoIra1 is involved in infection-related morphogenesis by regulating cAMP and MAPK signaling pathways through CoRas2 in Colletotrichum orbiculare. PLoS One. 2014 Oct 2;9(9):e109045. doi: 10.1371/journal.pone.0109045. eCollection, 2014. PMID:25275394 doi:http://dx.doi.org/10.1371/journal.pone.0109045

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Michal Harel, Alexander Berchansky

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