8u5y
From Proteopedia
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m (Protected "8u5y" [edit=sysop:move=sysop]) |
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- | '''Unreleased structure''' | ||
- | + | ==human RADX trimer bound to ssDNA== | |
- | + | <StructureSection load='8u5y' size='340' side='right'caption='[[8u5y]], [[Resolution|resolution]] 3.01Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[8u5y]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8U5Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8U5Y FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.01Å</td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8u5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8u5y OCA], [https://pdbe.org/8u5y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8u5y RCSB], [https://www.ebi.ac.uk/pdbsum/8u5y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8u5y ProSAT]</span></td></tr> |
- | [[Category: Balakrishnan | + | </table> |
- | [[Category: Chazin | + | == Function == |
+ | [https://www.uniprot.org/uniprot/RADX_HUMAN RADX_HUMAN] Single-stranded DNA-binding protein recruited to replication forks to maintain genome stability (PubMed:28735897). Prevents fork collapse by antagonizing the accumulation of RAD51 at forks to ensure the proper balance of fork remodeling and protection without interfering with the capacity of cells to complete homologous recombination of double-strand breaks (PubMed:28735897).<ref>PMID:28735897</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Balakrishnan S]] | ||
+ | [[Category: Chazin WJ]] |
Current revision
human RADX trimer bound to ssDNA
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