6ndn

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Current revision (06:51, 11 October 2023) (edit) (undo)
 
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<StructureSection load='6ndn' size='340' side='right'caption='[[6ndn]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
<StructureSection load='6ndn' size='340' side='right'caption='[[6ndn]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6ndn]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NDN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NDN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6ndn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_UMEA_3718-1 Escherichia coli UMEA 3718-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NDN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6NDN FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.768&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ndn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ndn OCA], [http://pdbe.org/6ndn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ndn RCSB], [http://www.ebi.ac.uk/pdbsum/6ndn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ndn ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ndn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ndn OCA], [https://pdbe.org/6ndn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ndn RCSB], [https://www.ebi.ac.uk/pdbsum/6ndn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ndn ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/T9SRD8_ECOLX T9SRD8_ECOLX]] Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine. Selenocysteine lyase activity is however unsure in vivo.[HAMAP-Rule:MF_01831][RuleBase:RU004506]
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==See Also==
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*[[Cysteine desulfurase 3D structures|Cysteine desulfurase 3D structures]]
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*[[Selenocysteine lyase|Selenocysteine lyase]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Escherichia coli UMEA 3718-1]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Brandao-Neto, J]]
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[[Category: Brandao-Neto J]]
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[[Category: Pereira, H M]]
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[[Category: Pereira HM]]
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[[Category: Scortecci, J F]]
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[[Category: Scortecci JF]]
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[[Category: Thiemann, O H]]
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[[Category: Thiemann OH]]
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[[Category: Enzyme]]
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[[Category: Lyase]]
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[[Category: Selenocysteine lyase]]
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Current revision

Crystal Structure of Selenocysteine Lyase from Escherichia coli

PDB ID 6ndn

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