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6okc

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Current revision (07:12, 11 October 2023) (edit) (undo)
 
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<StructureSection load='6okc' size='340' side='right'caption='[[6okc]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
<StructureSection load='6okc' size='340' side='right'caption='[[6okc]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6okc]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OKC OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6OKC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6okc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OKC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6OKC FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MRJ:N-[2-(dodecanoylamino)ethyl]-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide'>MRJ</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fabB, fabC, b2323, JW2320 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI]), acpP, b1094, JW1080 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MRJ:N-[2-(dodecanoylamino)ethyl]-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide'>MRJ</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-ketoacyl-[acyl-carrier-protein]_synthase_I Beta-ketoacyl-[acyl-carrier-protein] synthase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.41 2.3.1.41] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6okc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6okc OCA], [https://pdbe.org/6okc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6okc RCSB], [https://www.ebi.ac.uk/pdbsum/6okc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6okc ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6okc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6okc OCA], [http://pdbe.org/6okc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6okc RCSB], [http://www.ebi.ac.uk/pdbsum/6okc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6okc ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/FABB_ECOLI FABB_ECOLI]] Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids. [[http://www.uniprot.org/uniprot/ACP_ECOLI ACP_ECOLI]] Carrier of the growing fatty acid chain in fatty acid biosynthesis.[HAMAP-Rule:MF_01217]
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[https://www.uniprot.org/uniprot/FABB_ECOLI FABB_ECOLI] Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6okc" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6okc" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Acyl carrier protein 3D structures|Acyl carrier protein 3D structures]]
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*[[Acyl carrier protein synthase 3D structures|Acyl carrier protein synthase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ecoli]]
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[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Bartholow, T G]]
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[[Category: Bartholow TG]]
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[[Category: Burkart, M D]]
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[[Category: Burkart MD]]
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[[Category: Chen, A]]
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[[Category: Chen A]]
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[[Category: Clair, J La]]
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[[Category: Davis TD]]
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[[Category: Davis, T D]]
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[[Category: Kim WE]]
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[[Category: Kim, W E]]
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[[Category: La Clair J]]
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[[Category: Mindrebo, J T]]
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[[Category: Mindrebo JT]]
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[[Category: Noel, J P]]
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[[Category: Noel JP]]
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[[Category: Acpp]]
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[[Category: Ketosynthase]]
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[[Category: Thiolase]]
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[[Category: Transferase-lipid transport complex]]
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Current revision

Crosslinked Crystal Structure of Type II Fatty Acid Synthase Ketosynthase, FabB, and C12-crypto Acyl Carrier Protein, AcpP

PDB ID 6okc

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