6opv

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Current revision (07:15, 11 October 2023) (edit) (undo)
 
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<StructureSection load='6opv' size='340' side='right'caption='[[6opv]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
<StructureSection load='6opv' size='340' side='right'caption='[[6opv]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6opv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OPV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6OPV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6opv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OPV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6OPV FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=017:(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE'>017</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.91&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 9HIV1])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=017:(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE'>017</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6opv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6opv OCA], [http://pdbe.org/6opv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6opv RCSB], [http://www.ebi.ac.uk/pdbsum/6opv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6opv ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6opv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6opv OCA], [https://pdbe.org/6opv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6opv RCSB], [https://www.ebi.ac.uk/pdbsum/6opv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6opv ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q7ZCI0_9HIV1 Q7ZCI0_9HIV1]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human immunodeficiency virus 1]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Bolon, D N.A]]
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[[Category: Bolon DNA]]
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[[Category: Henes, M]]
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[[Category: Henes M]]
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[[Category: Kosovrasti, K]]
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[[Category: Kosovrasti K]]
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[[Category: KurtYilmaz, N]]
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[[Category: KurtYilmaz N]]
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[[Category: Leidner, F]]
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[[Category: Leidner F]]
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[[Category: Lockbaum, G J]]
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[[Category: Lockbaum GJ]]
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[[Category: Nachum, G S]]
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[[Category: Nachum GS]]
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[[Category: Nalivaika, E A]]
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[[Category: Nalivaika EA]]
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[[Category: Schiffer, C A]]
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[[Category: Schiffer CA]]
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[[Category: Drug resistance]]
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[[Category: Hiv]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase inhibitor complex]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Nl4-3 protease]]
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[[Category: Protease inhibitor]]
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Current revision

HIV-1 Protease NL4-3 I13V, G16E, V32I, L33F, K45I, M46I, V82F, I84V Mutant in complex with darunavir

PDB ID 6opv

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