6p04

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Current revision (07:20, 11 October 2023) (edit) (undo)
 
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<StructureSection load='6p04' size='340' side='right'caption='[[6p04]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='6p04' size='340' side='right'caption='[[6p04]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6p04]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacsp Bacsp]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6P04 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6P04 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6p04]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_sp._(in:_Bacteria) Bacillus sp. (in: Bacteria)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6P04 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6P04 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NMY:NEOMYCIN'>NMY</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6nlt|6nlt]], [[6nmk|6nmk]], [[6nml|6nml]], [[6nmm|6nmm]], [[6nmn|6nmn]], [[6poi|6poi]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NMY:NEOMYCIN'>NMY</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">knt, kan ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1409 BACSP])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6p04 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6p04 OCA], [https://pdbe.org/6p04 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6p04 RCSB], [https://www.ebi.ac.uk/pdbsum/6p04 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6p04 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6p04 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6p04 OCA], [http://pdbe.org/6p04 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6p04 RCSB], [http://www.ebi.ac.uk/pdbsum/6p04 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6p04 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/KANU_BACSP KANU_BACSP]] Inactivates the antibiotic kanamycin by catalyzing the transfer of a nucleotidyl group from nucleoside triphosphates such as ATP to the 4'-hydroxyl group of the aminoglycoside.
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[https://www.uniprot.org/uniprot/KANU_BACSP KANU_BACSP] Inactivates the antibiotic kanamycin by catalyzing the transfer of a nucleotidyl group from nucleoside triphosphates such as ATP to the 4'-hydroxyl group of the aminoglycoside.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacsp]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Cuneo, M J]]
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[[Category: Cuneo MJ]]
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[[Category: Selvaraj, B]]
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[[Category: Selvaraj B]]
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[[Category: Antibiotic]]
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[[Category: Dna polymerase]]
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[[Category: Transferase-antibiotic complex]]
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Current revision

Binary structure of the E52D mutant of ANT-4 with Neomycin

PDB ID 6p04

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