6p1y

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Current revision (07:21, 11 October 2023) (edit) (undo)
 
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<StructureSection load='6p1y' size='340' side='right'caption='[[6p1y]], [[Resolution|resolution]] 2.33&Aring;' scene=''>
<StructureSection load='6p1y' size='340' side='right'caption='[[6p1y]], [[Resolution|resolution]] 2.33&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6p1y]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6P1Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6P1Y FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6p1y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6P1Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6P1Y FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.33&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aspartate_1-decarboxylase Aspartate 1-decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.11 4.1.1.11] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6p1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6p1y OCA], [https://pdbe.org/6p1y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6p1y RCSB], [https://www.ebi.ac.uk/pdbsum/6p1y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6p1y ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6p1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6p1y OCA], [http://pdbe.org/6p1y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6p1y RCSB], [http://www.ebi.ac.uk/pdbsum/6p1y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6p1y ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PAND_MYCTU PAND_MYCTU]] Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity).
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[https://www.uniprot.org/uniprot/PAND_MYCTU PAND_MYCTU] Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6p1y" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6p1y" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Aspartate decarboxylase 3D structures|Aspartate decarboxylase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Aspartate 1-decarboxylase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Li, X]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Sacchettini, J C]]
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[[Category: Li X]]
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[[Category: Sun, Q]]
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[[Category: Sacchettini JC]]
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[[Category: Structural genomic]]
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[[Category: Sun Q]]
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[[Category: Drug-resistance]]
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[[Category: Lyase]]
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[[Category: Mutant]]
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[[Category: Poa]]
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[[Category: Tbsgc]]
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Current revision

Crystal structure of Mtb aspartate decarboxylase mutant M117I

PDB ID 6p1y

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