6p22

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==Photorhabdus Virulence Cassette (PVC) PAAR repeat protein Pvc10 in complex with a T4 gp5 beta-helix fragment modified to mimic Pvc8, the central spike protein of PVC==
==Photorhabdus Virulence Cassette (PVC) PAAR repeat protein Pvc10 in complex with a T4 gp5 beta-helix fragment modified to mimic Pvc8, the central spike protein of PVC==
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<StructureSection load='6p22' size='340' side='right'caption='[[6p22]]' scene=''>
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<StructureSection load='6p22' size='340' side='right'caption='[[6p22]], [[Resolution|resolution]] 2.29&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6P22 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6P22 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6p22]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4] and [https://en.wikipedia.org/wiki/Photorhabdus_laumondii_subsp._laumondii_TTO1 Photorhabdus laumondii subsp. laumondii TTO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6P22 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6P22 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6p22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6p22 OCA], [http://pdbe.org/6p22 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6p22 RCSB], [http://www.ebi.ac.uk/pdbsum/6p22 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6p22 ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.291&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ELA:9-OCTADECENOIC+ACID'>ELA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene>, <scene name='pdbligand=STE:STEARIC+ACID'>STE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6p22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6p22 OCA], [https://pdbe.org/6p22 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6p22 RCSB], [https://www.ebi.ac.uk/pdbsum/6p22 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6p22 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q7N647_PHOLL Q7N647_PHOLL] [https://www.uniprot.org/uniprot/NEEDL_BPT4 NEEDL_BPT4] Tail-associated lysozyme of the baseplate hub that is essential for localized hydrolysis of bacterial cell wall necessary for viral DNA injection. The needle-like gp5 protein punctures the outer cell membrane and then digests the peptidoglycan cell wall in the periplasmic space. Involved in the tail assembly.<ref>PMID:12837775</ref> <ref>PMID:21129200</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Escherichia virus T4]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Photorhabdus laumondii subsp. laumondii TTO1]]
[[Category: Buth SA]]
[[Category: Buth SA]]
[[Category: Leiman PG]]
[[Category: Leiman PG]]
[[Category: Shneider MM]]
[[Category: Shneider MM]]

Revision as of 07:21, 11 October 2023

Photorhabdus Virulence Cassette (PVC) PAAR repeat protein Pvc10 in complex with a T4 gp5 beta-helix fragment modified to mimic Pvc8, the central spike protein of PVC

PDB ID 6p22

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