6pku

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Current revision (07:31, 11 October 2023) (edit) (undo)
 
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<StructureSection load='6pku' size='340' side='right'caption='[[6pku]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='6pku' size='340' side='right'caption='[[6pku]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6pku]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Cavpo Cavpo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PKU OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6PKU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6pku]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Cavia_porcellus Cavia porcellus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PKU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PKU FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=M6P:ALPHA-D-MANNOSE-6-PHOSPHATE'>M6P</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.949&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NAGPA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10141 CAVPO])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=M6P:ALPHA-D-MANNOSE-6-PHOSPHATE'>M6P</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6pku FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pku OCA], [http://pdbe.org/6pku PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pku RCSB], [http://www.ebi.ac.uk/pdbsum/6pku PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pku ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pku FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pku OCA], [https://pdbe.org/6pku PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pku RCSB], [https://www.ebi.ac.uk/pdbsum/6pku PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pku ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/H0VTT5_CAVPO H0VTT5_CAVPO]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Cavpo]]
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[[Category: Cavia porcellus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Gorelik, A]]
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[[Category: Gorelik A]]
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[[Category: Illes, K]]
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[[Category: Illes K]]
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[[Category: Nagar, B]]
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[[Category: Nagar B]]
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[[Category: Glycosidase]]
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[[Category: Hydrolase]]
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[[Category: Mannose 6-phosphate]]
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[[Category: N-acetylglucosamine]]
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[[Category: Uncovering enzyme]]
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Current revision

Guinea pig N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (NAGPA) catalytic domain (C51S C221S) in complex with N-acetyl-alpha-D-glucosamine (alpha-GlcNAc) and mannose 6-phosphate (M6P)

PDB ID 6pku

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