3b18
From Proteopedia
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<StructureSection load='3b18' size='340' side='right'caption='[[3b18]], [[Resolution|resolution]] 2.75Å' scene=''>  | <StructureSection load='3b18' size='340' side='right'caption='[[3b18]], [[Resolution|resolution]] 2.75Å' scene=''>  | ||
== Structural highlights ==  | == Structural highlights ==  | ||
| - | <table><tr><td colspan='2'>[[3b18]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/  | + | <table><tr><td colspan='2'>[[3b18]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B18 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B18 FirstGlance]. <br>  | 
| - | </td></tr><tr id='  | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75Å</td></tr>  | 
| - | <tr id='  | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DAO:LAURIC+ACID'>DAO</scene></td></tr>  | 
| - | + | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b18 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b18 OCA], [https://pdbe.org/3b18 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b18 RCSB], [https://www.ebi.ac.uk/pdbsum/3b18 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b18 ProSAT]</span></td></tr>  | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b18 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b18 OCA], [https://pdbe.org/3b18 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b18 RCSB], [https://www.ebi.ac.uk/pdbsum/3b18 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b18 ProSAT]</span></td></tr>  | ||
</table>  | </table>  | ||
| + | == Function ==  | ||
| + | [https://www.uniprot.org/uniprot/FCOT_MYCTU FCOT_MYCTU] Thiesterase that shows a preference for long chain fatty acyl groups. In vitro, cleaves the thioester linkage of palmitoyl-CoA, stearoyl-CoA, lauroyl-CoA and hexanoyl-CoA (PubMed:17524985). Contains low levels of trans-enoyl hydratase activity (PubMed:19136596).<ref>PMID:17524985</ref> <ref>PMID:19136596</ref>   | ||
<div style="background-color:#fffaf0;">  | <div style="background-color:#fffaf0;">  | ||
== Publication Abstract from PubMed ==  | == Publication Abstract from PubMed ==  | ||
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</StructureSection>  | </StructureSection>  | ||
[[Category: Large Structures]]  | [[Category: Large Structures]]  | ||
| - | [[Category: Maity, K]]  | ||
| - | [[Category: Suguna, K]]  | ||
| - | [[Category: Acyl carrier protein]]  | ||
| - | [[Category: Hot dog fold]]  | ||
| - | [[Category: Hydrolase]]  | ||
| - | [[Category: Long-chain fatty acyl-coa thioesterase]]  | ||
[[Category: Mycobacterium tuberculosis]]  | [[Category: Mycobacterium tuberculosis]]  | ||
| + | [[Category: Maity K]]  | ||
| + | [[Category: Suguna K]]  | ||
Revision as of 08:51, 11 October 2023
Rv0098 of Mycobacterium tuberculosis with ordered loop between beta-4 and beta-5
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