3a7o

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Current revision (14:13, 18 October 2023) (edit) (undo)
 
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<StructureSection load='3a7o' size='340' side='right'caption='[[3a7o]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='3a7o' size='340' side='right'caption='[[3a7o]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3a7o]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A7O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3A7O FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3a7o]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A7O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3A7O FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3a7p|3a7p]]</div></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ATG16 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3a7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a7o OCA], [https://pdbe.org/3a7o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3a7o RCSB], [https://www.ebi.ac.uk/pdbsum/3a7o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3a7o ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3a7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a7o OCA], [https://pdbe.org/3a7o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3a7o RCSB], [https://www.ebi.ac.uk/pdbsum/3a7o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3a7o ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/ATG16_YEAST ATG16_YEAST]] Stabilizes the ATG5-ATG12 conjugate and mediates the formation of the 350 kDa complex, which is necessary for autophagy. Required for ATG8 localization to the pre-autophagosomal structure.<ref>PMID:8224160</ref> <ref>PMID:8663607</ref> <ref>PMID:10406794</ref> <ref>PMID:11689437</ref> <ref>PMID:11897782</ref>
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[https://www.uniprot.org/uniprot/ATG16_YEAST ATG16_YEAST] Stabilizes the ATG5-ATG12 conjugate and mediates the formation of the 350 kDa complex, which is necessary for autophagy. Required for ATG8 localization to the pre-autophagosomal structure.<ref>PMID:8224160</ref> <ref>PMID:8663607</ref> <ref>PMID:10406794</ref> <ref>PMID:11689437</ref> <ref>PMID:11897782</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 18824]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Fujioka, Y]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Inagaki, F]]
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[[Category: Fujioka Y]]
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[[Category: Noda, N N]]
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[[Category: Inagaki F]]
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[[Category: Autophagy]]
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[[Category: Noda NN]]
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[[Category: Coiled coil]]
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[[Category: Coiled-coil]]
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[[Category: Cytoplasmic vesicle]]
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[[Category: Protein transport]]
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[[Category: Transport]]
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[[Category: Vacuole]]
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Current revision

The crystal structure of the coiled-coil domain of Saccharomyces cerevisiae Atg16

PDB ID 3a7o

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