6wep
From Proteopedia
(Difference between revisions)
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==Crystal structure of TS-DHFR from Cryptosporidium hominis with Apo-TS site== | ==Crystal structure of TS-DHFR from Cryptosporidium hominis with Apo-TS site== | ||
| - | <StructureSection load='6wep' size='340' side='right'caption='[[6wep]]' scene=''> | + | <StructureSection load='6wep' size='340' side='right'caption='[[6wep]], [[Resolution|resolution]] 2.79Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WEP OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[6wep]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_hominis Cryptosporidium hominis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WEP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WEP FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.79Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MTX:METHOTREXATE'>MTX</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wep FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wep OCA], [https://pdbe.org/6wep PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wep RCSB], [https://www.ebi.ac.uk/pdbsum/6wep PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wep ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A0S4TER9_CRYHO A0A0S4TER9_CRYHO] Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism.[PIRNR:PIRNR000389] | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Cryptosporidium hominis]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Anderson KS]] | [[Category: Anderson KS]] | ||
Current revision
Crystal structure of TS-DHFR from Cryptosporidium hominis with Apo-TS site
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