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7k2y

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Current revision (15:16, 18 October 2023) (edit) (undo)
 
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<StructureSection load='7k2y' size='340' side='right'caption='[[7k2y]], [[Resolution|resolution]] 1.62&Aring;' scene=''>
<StructureSection load='7k2y' size='340' side='right'caption='[[7k2y]], [[Resolution|resolution]] 1.62&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[7k2y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7K2Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7K2Y FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7k2y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7K2Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7K2Y FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AIX:(2R,4S)-2-[(1R)-1-{[(2R)-2-AMINO-2-PHENYLACETYL]AMINO}-2-OXOETHYL]-5,5-DIMETHYL-1,3-THIAZOLIDINE-4-CARBOXYLIC+ACID'>AIX</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.62&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">blaCTX-M ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AIX:(2R,4S)-2-[(1R)-1-{[(2R)-2-AMINO-2-PHENYLACETYL]AMINO}-2-OXOETHYL]-5,5-DIMETHYL-1,3-THIAZOLIDINE-4-CARBOXYLIC+ACID'>AIX</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7k2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7k2y OCA], [https://pdbe.org/7k2y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7k2y RCSB], [https://www.ebi.ac.uk/pdbsum/7k2y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7k2y ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7k2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7k2y OCA], [https://pdbe.org/7k2y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7k2y RCSB], [https://www.ebi.ac.uk/pdbsum/7k2y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7k2y ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q9L5C7_ECOLX Q9L5C7_ECOLX]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
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[[Category: Beta-lactamase]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Hu, L]]
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[[Category: Hu L]]
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[[Category: Lu, S]]
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[[Category: Lu S]]
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[[Category: Palzkill, T]]
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[[Category: Palzkill T]]
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[[Category: Prasad, B V.V]]
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[[Category: Prasad BVV]]
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[[Category: Sankaran, B]]
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[[Category: Sankaran B]]
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[[Category: Soeung, V]]
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[[Category: Soeung V]]
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[[Category: Acyl-enzyme intermediate]]
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[[Category: Antibiotic resistance]]
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[[Category: Hydrolase]]
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Current revision

Crystal structure of CTX-M-14 E166A/K234R Beta-lactamase in complex with hydrolyzed ampicillin

PDB ID 7k2y

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