This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


7kh8

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:24, 18 October 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='7kh8' size='340' side='right'caption='[[7kh8]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
<StructureSection load='7kh8' size='340' side='right'caption='[[7kh8]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[7kh8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KH8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KH8 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[7kh8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KH8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KH8 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=WE7:3-[(2,6-dichlorophenyl)methyl]-8-(2-methylphenyl)-3H-purin-6-amine'>WE7</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ACP1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=WE7:3-[(2,6-dichlorophenyl)methyl]-8-(2-methylphenyl)-3H-purin-6-amine'>WE7</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kh8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kh8 OCA], [https://pdbe.org/7kh8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kh8 RCSB], [https://www.ebi.ac.uk/pdbsum/7kh8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kh8 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kh8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kh8 OCA], [https://pdbe.org/7kh8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kh8 RCSB], [https://www.ebi.ac.uk/pdbsum/7kh8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kh8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/PPAC_HUMAN PPAC_HUMAN]] Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Isoform 3 does not possess phosphatase activity.
+
[https://www.uniprot.org/uniprot/PPAC_HUMAN PPAC_HUMAN] Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Isoform 3 does not possess phosphatase activity.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 19: Line 19:
</div>
</div>
<div class="pdbe-citations 7kh8" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 7kh8" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Ardecky, R J]]
+
[[Category: Ardecky RJ]]
-
[[Category: Bottini, N]]
+
[[Category: Bottini N]]
-
[[Category: Chung, T D.Y]]
+
[[Category: Chung TDY]]
-
[[Category: Diaz, M A]]
+
[[Category: Diaz MA]]
-
[[Category: Hedrick, M P]]
+
[[Category: Hedrick MP]]
-
[[Category: Holmes, Z J]]
+
[[Category: Holmes ZJ]]
-
[[Category: Jackson, M R]]
+
[[Category: Jackson MR]]
-
[[Category: Pinkerton, A B]]
+
[[Category: Pinkerton AB]]
-
[[Category: Rodiles, S]]
+
[[Category: Rodiles S]]
-
[[Category: Roosild, T]]
+
[[Category: Roosild T]]
-
[[Category: Santelli, E]]
+
[[Category: Santelli E]]
-
[[Category: Stanford, S M]]
+
[[Category: Stanford SM]]
-
[[Category: Zou, J]]
+
[[Category: Zou J]]
-
[[Category: Complex]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Hydrolase-hydrolase inhibitor complex]]
+
-
[[Category: Inhibitor]]
+
-
[[Category: Lmwptp]]
+
-
[[Category: Protein tyrosine phosphatase]]
+

Current revision

Human LMPTP in complex with inhibitor

PDB ID 7kh8

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/7kh8"
Personal tools