7kl2
From Proteopedia
(Difference between revisions)
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| - | ==== | + | ==Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B(S1303D)== |
| - | <StructureSection load='7kl2' size='340' side='right'caption='[[7kl2]]' scene=''> | + | <StructureSection load='7kl2' size='340' side='right'caption='[[7kl2]], [[Resolution|resolution]] 2.56Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7kl2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KL2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KL2 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kl2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kl2 OCA], [https://pdbe.org/7kl2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kl2 RCSB], [https://www.ebi.ac.uk/pdbsum/7kl2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kl2 ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.56Å</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kl2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kl2 OCA], [https://pdbe.org/7kl2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kl2 RCSB], [https://www.ebi.ac.uk/pdbsum/7kl2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kl2 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/KCC2A_HUMAN KCC2A_HUMAN] CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity). | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Calcium/calmodulin dependent protein kinase 3D structures|Calcium/calmodulin dependent protein kinase 3D structures]] | ||
| + | *[[Glutamate receptor 3D structures|Glutamate receptor 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Garman SC]] |
| + | [[Category: Ozden C]] | ||
| + | [[Category: Stratton MM]] | ||
Current revision
Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B(S1303D)
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