7krv

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<StructureSection load='7krv' size='340' side='right'caption='[[7krv]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
<StructureSection load='7krv' size='340' side='right'caption='[[7krv]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[7krv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KRV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KRV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7krv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KRV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KRV FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6LN:ETHANE-1,2-DITHIOL'>6LN</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.92&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[7kru|7kru]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6LN:ETHANE-1,2-DITHIOL'>6LN</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7krv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7krv OCA], [https://pdbe.org/7krv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7krv RCSB], [https://www.ebi.ac.uk/pdbsum/7krv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7krv ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7krv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7krv OCA], [https://pdbe.org/7krv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7krv RCSB], [https://www.ebi.ac.uk/pdbsum/7krv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7krv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/A0A6D2W465_ECOLI A0A6D2W465_ECOLI]] Acts as a chaperone.[HAMAP-Rule:MF_00332]
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[https://www.uniprot.org/uniprot/DNAK_ECOLI DNAK_ECOLI] Plays an essential role in the initiation of phage lambda DNA replication, where it acts in an ATP-dependent fashion with the DnaJ protein to release lambda O and P proteins from the preprimosomal complex. DnaK is also involved in chromosomal DNA replication, possibly through an analogous interaction with the DnaA protein. Also participates actively in the response to hyperosmotic shock.[HAMAP-Rule:MF_00332]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 7krv" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 7krv" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Heat Shock Protein structures|Heat Shock Protein structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Hendrickson, W A]]
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[[Category: Hendrickson WA]]
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[[Category: Wang, W]]
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[[Category: Wang W]]
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[[Category: Chaperone]]
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[[Category: Hsp70]]
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[[Category: Molecular chaperone]]
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[[Category: Protein folding]]
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Revision as of 15:30, 18 October 2023

Stimulating state of disulfide-bridged Hsp70 DnaK

PDB ID 7krv

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