7lta
From Proteopedia
(Difference between revisions)
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==Galectin-1 in complex with Trehalose== | ==Galectin-1 in complex with Trehalose== | ||
| - | <StructureSection load='7lta' size='340' side='right'caption='[[7lta]]' scene=''> | + | <StructureSection load='7lta' size='340' side='right'caption='[[7lta]], [[Resolution|resolution]] 1.53Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LTA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LTA FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7lta]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LTA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LTA FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lta OCA], [https://pdbe.org/7lta PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lta RCSB], [https://www.ebi.ac.uk/pdbsum/7lta PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lta ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.53Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lta OCA], [https://pdbe.org/7lta PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lta RCSB], [https://www.ebi.ac.uk/pdbsum/7lta PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lta ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/LEG1_HUMAN LEG1_HUMAN] May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase.<ref>PMID:14617626</ref> <ref>PMID:18796645</ref> | ||
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| + | ==See Also== | ||
| + | *[[Galectin 3D structures|Galectin 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Bechold J]] | [[Category: Bechold J]] | ||
[[Category: Grimm C]] | [[Category: Grimm C]] | ||
[[Category: Seibel J]] | [[Category: Seibel J]] | ||
Revision as of 15:58, 18 October 2023
Galectin-1 in complex with Trehalose
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