7lun

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<StructureSection load='7lun' size='340' side='right'caption='[[7lun]], [[Resolution|resolution]] 2.57&Aring;' scene=''>
<StructureSection load='7lun' size='340' side='right'caption='[[7lun]], [[Resolution|resolution]] 2.57&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[7lun]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LUN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LUN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7lun]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LUN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LUN FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=YFG:7-(cyclopentylamino)-5-fluoro-2-{[(trans-4-hydroxycyclohexyl)sulfanyl]methyl}quinazolin-4(3H)-one'>YFG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.57&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PARP14, BAL2, KIAA1268 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=YFG:7-(cyclopentylamino)-5-fluoro-2-{[(trans-4-hydroxycyclohexyl)sulfanyl]methyl}quinazolin-4(3H)-one'>YFG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lun FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lun OCA], [https://pdbe.org/7lun PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lun RCSB], [https://www.ebi.ac.uk/pdbsum/7lun PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lun ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lun FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lun OCA], [https://pdbe.org/7lun PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lun RCSB], [https://www.ebi.ac.uk/pdbsum/7lun PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lun ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/PAR14_HUMAN PAR14_HUMAN]] Enhances STAT6-dependent transcription (By similarity). Has ADP-ribosyltransferase activity.
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[https://www.uniprot.org/uniprot/PAR14_HUMAN PAR14_HUMAN] Enhances STAT6-dependent transcription (By similarity). Has ADP-ribosyltransferase activity.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 7lun" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 7lun" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Poly(ADP-ribose) polymerase 3D structures|Poly(ADP-ribose) polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Church, W D]]
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[[Category: Church WD]]
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[[Category: Dorsey, B W]]
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[[Category: Dorsey BW]]
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[[Category: Kuntz, K W]]
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[[Category: Kuntz KW]]
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[[Category: Perl, N R]]
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[[Category: Perl NR]]
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[[Category: Schenkel, L B]]
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[[Category: Schenkel LB]]
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[[Category: Swinger, K K]]
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[[Category: Swinger KK]]
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[[Category: Vasbinder, M M]]
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[[Category: Vasbinder MM]]
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[[Category: Wigle, T J]]
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[[Category: Wigle TJ]]
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[[Category: Adp ribosylation]]
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[[Category: Artd8]]
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[[Category: Inhibitor complex]]
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[[Category: Monoparp]]
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[[Category: Parp14]]
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[[Category: Transferase]]
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[[Category: Transferase-inhibitor complex]]
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Revision as of 16:00, 18 October 2023

Human PARP14 (ARTD8), catalytic fragment in complex with RBN011980

PDB ID 7lun

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