7rue

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Current revision (16:39, 18 October 2023) (edit) (undo)
 
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<StructureSection load='7rue' size='340' side='right'caption='[[7rue]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='7rue' size='340' side='right'caption='[[7rue]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[7rue]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RUE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RUE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7rue]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RUE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RUE FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7QH:(2E)-2-(2-carbamoylhydrazinylidene)-3,3,3-trifluoropropanoic+acid'>7QH</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/3-deoxy-7-phosphoheptulonate_synthase 3-deoxy-7-phosphoheptulonate synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.54 2.5.1.54] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7QH:(2E)-2-(2-carbamoylhydrazinylidene)-3,3,3-trifluoropropanoic+acid'>7QH</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rue FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rue OCA], [https://pdbe.org/7rue PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rue RCSB], [https://www.ebi.ac.uk/pdbsum/7rue PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rue ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rue FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rue OCA], [https://pdbe.org/7rue PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rue RCSB], [https://www.ebi.ac.uk/pdbsum/7rue PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rue ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/AROG_ECOLI AROG_ECOLI]] Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).
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[https://www.uniprot.org/uniprot/AROG_ECOLI AROG_ECOLI] Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 7rue" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 7rue" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[DAHP synthase 3D structures|DAHP synthase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 3-deoxy-7-phosphoheptulonate synthase]]
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[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Berti, P J]]
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[[Category: Berti PJ]]
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[[Category: Brown, C]]
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[[Category: Brown C]]
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[[Category: Grainger, R]]
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[[Category: Grainger R]]
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[[Category: Heimhalt, M]]
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[[Category: Heimhalt M]]
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[[Category: Junop, M S]]
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[[Category: Junop MS]]
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[[Category: Mukherjee, P]]
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[[Category: Mukherjee P]]
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[[Category: Szabla, R]]
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[[Category: Szabla R]]
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[[Category: Turner, R]]
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[[Category: Turner R]]
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[[Category: Dahp synthase]]
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[[Category: Inhibitor complex]]
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[[Category: Lyase]]
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[[Category: Transferase-transferase inhibitor complex]]
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Current revision

DAHP synthase complexed with trifluoropyruvate semicarbazone

PDB ID 7rue

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